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Research ArticleMinireview

Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling

Ee Von Moo, Jeffrey R. van Senten, Hans Bräuner-Osborne and Thor C. Møller
Molecular Pharmacology April 2021, 99 (4) 242-255; DOI: https://doi.org/10.1124/molpharm.120.000192
Ee Von Moo
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Jeffrey R. van Senten
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Hans Bräuner-Osborne
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Thor C. Møller
Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
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Article Information

vol. 99 no. 4 242-255
DOI 
https://doi.org/10.1124/molpharm.120.000192
PubMed 
33472843

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 27, 2020
  • Accepted January 7, 2021
  • Published online March 15, 2021.

Article Versions

  • Earlier version (January 20, 2021 - 11:11).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ee Von Moo,
  2. Jeffrey R. van Senten,
  3. Hans Bräuner-Osborne, and
  4. Thor C. Møller
  1. Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
  1. Address correspondence to:
    Thor C. Møller, Universitetsparken 2, 2100 Copenhagen, Denmark. E-mail: thor.moller{at}sund.ku.dk
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Article usage: January 2021 to April 2021

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Jan 20215610211
Feb 20212640161
Mar 202167471134
Apr 20214912732

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Molecular Pharmacology: 99 (4)
Molecular Pharmacology
Vol. 99, Issue 4
1 Apr 2021
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Research ArticleMinireview

Arrestin-Dependent and -Independent Internalization of GPCRs

Ee Von Moo, Jeffrey R. van Senten, Hans Bräuner-Osborne and Thor C. Møller
Molecular Pharmacology April 1, 2021, 99 (4) 242-255; DOI: https://doi.org/10.1124/molpharm.120.000192

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Research ArticleMinireview

Arrestin-Dependent and -Independent Internalization of GPCRs

Ee Von Moo, Jeffrey R. van Senten, Hans Bräuner-Osborne and Thor C. Møller
Molecular Pharmacology April 1, 2021, 99 (4) 242-255; DOI: https://doi.org/10.1124/molpharm.120.000192
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  • Article
    • Abstract
    • Introduction
    • Clathrin-Mediated Endocytosis
    • Clathrin-Independent Endocytosis
    • Arrestin-Independent Agonist-Induced Endocytosis
    • Arrestin-Independent Constitutive Endocytosis
    • Methods for Measuring Endocytosis
    • Conclusions
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
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