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Research ArticleSpecial Section on Phosphoproteomic Analysis of G Protein-Coupled Pathways - Axelrod Symposium—Minireview
Open Access

Phosphoproteomics-Based Characterization of Prostaglandin E2 Signaling in T Cells

Anna Mari Lone and Kjetil Taskén
Molecular Pharmacology May 2021, 99 (5) 370-382; DOI: https://doi.org/10.1124/molpharm.120.000170
Anna Mari Lone
Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital (A.M.L., K.T.) and Institute for Clinical Medicine, University of Oslo, Oslo, Norway (K.T.)
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Kjetil Taskén
Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital (A.M.L., K.T.) and Institute for Clinical Medicine, University of Oslo, Oslo, Norway (K.T.)
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Molecular Pharmacology: 99 (5)
Molecular Pharmacology
Vol. 99, Issue 5
1 May 2021
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Research ArticleSpecial Section on Phosphoproteomic Analysis of G Protein-Coupled Pathways - Axelrod Symposium—Minireview

PGE2 Signaling in T Cells

Anna Mari Lone and Kjetil Taskén
Molecular Pharmacology May 1, 2021, 99 (5) 370-382; DOI: https://doi.org/10.1124/molpharm.120.000170

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Research ArticleSpecial Section on Phosphoproteomic Analysis of G Protein-Coupled Pathways - Axelrod Symposium—Minireview

PGE2 Signaling in T Cells

Anna Mari Lone and Kjetil Taskén
Molecular Pharmacology May 1, 2021, 99 (5) 370-382; DOI: https://doi.org/10.1124/molpharm.120.000170
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  • Article
    • Abstract
    • Introduction
    • Phosphoproteomics and Its Application to Signaling Studies
    • Phosphoproteomics Studies of PGE2 Signaling in T Cells
    • PKA Signaling and Interaction with TCR Signaling
    • Non-PKA Signaling Nodes and Pathways
    • Signaling Networks Regulated by PGE2
    • Distinct PGE2 Responses Across T Cell Subtypes
    • Temporal Patterns in PGE2 Signaling
    • Functional Output of PGE2 Signaling in T Cells
    • Perspectives and Future Directions
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
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