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Molecular Pharmacology

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Table of Contents

June 01, 2021; Volume 99,Issue 6

Minireview

  • Update on Angiotensin II Subtype 2 Receptor: Focus on Peptide and Nonpeptide Agonists
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    Update on Angiotensin II Subtype 2 Receptor: Focus on Peptide and Nonpeptide Agonists
    Arina Ranjit, Sana Khajehpour and Ali Aghazadeh-Habashi
    Molecular Pharmacology June 2021, 99 (6) 469-487; DOI: https://doi.org/10.1124/molpharm.121.000236

Articles

  • Inhibition of Human Uracil DNA Glycosylase Sensitizes a Large Fraction of Colorectal Cancer Cells to 5-Fluorodeoxyuridine and Raltitrexed but Not Fluorouracil
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    Inhibition of Human Uracil DNA Glycosylase Sensitizes a Large Fraction of Colorectal Cancer Cells to 5-Fluorodeoxyuridine and Raltitrexed but Not Fluorouracil
    Eric S. Christenson, Anthony Gizzi, Junru Cui, Matthew Egleston, Kyle J. Seamon, Michael DePasquale, Benjamin Orris, Ben H. Park and James T. Stivers
    Molecular Pharmacology June 2021, 99 (6) 412-425; DOI: https://doi.org/10.1124/molpharm.120.000191
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    Substituted Cysteine Modification and Protection with n-Alkyl- Methanethiosulfonate Reagents Yields a Precise Estimate of the Distance between Etomidate and a Residue in Activated GABA Type A Receptors
    Ryan J. Fantasia, Anahita Nourmahnad, Elizabeth Halpin and Stuart A. Forman
    Molecular Pharmacology June 2021, 99 (6) 426-434; DOI: https://doi.org/10.1124/molpharm.120.000224
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    Novel Human-Derived RET Fusion NSCLC Cell Lines Have Heterogeneous Responses to RET Inhibitors and Differential Regulation of Downstream Signaling
    Laura Schubert, Anh T. Le, Adriana Estrada-Bernal, Andrea E. Doak, Minjae Yoo, Sarah E. Ferrara, Andrew Goodspeed, Fumi Kinose, Uwe Rix, Aik-Choon Tan and Robert C. Doebele
    Molecular Pharmacology June 2021, 99 (6) 435-447; DOI: https://doi.org/10.1124/molpharm.120.000207
  • Ethnic-Related Sodium Voltage-Gated Channel <em>α</em> Subunit 5 Polymorphisms Shape the In Vitro Pharmacological Action of Amiodarone upon Na<sub>v</sub>1.5
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    Ethnic-Related Sodium Voltage-Gated Channel α Subunit 5 Polymorphisms Shape the In Vitro Pharmacological Action of Amiodarone upon Nav1.5
    Julliane Vasconcelos Joviano-Santos, Artur Santos-Miranda, Jaqueline Oliveira Sarmento and Danilo Roman-Campos
    Molecular Pharmacology June 2021, 99 (6) 448-459; DOI: https://doi.org/10.1124/molpharm.120.000176
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    Identification of Chemical and Pharmacological Chaperones for Correction of Trafficking-Deficient Mutant Cyclic Nucleotide–Gated A3 Channels
    Joachim Täger, Bernd Wissinger, Susanne Kohl and Peggy Reuter
    Molecular Pharmacology June 2021, 99 (6) 460-468; DOI: https://doi.org/10.1124/molpharm.120.000180
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    Circular RNAs of UDP-Glycosyltransferase (UGT) Genes Expand the Complexity and Diversity of the UGT Transcriptome
    Dong Gui Hu, Peter I. Mackenzie, Julie-Ann Hulin, Ross A. McKinnon and Robyn Meech
    Molecular Pharmacology June 2021, 99 (6) 488-503; DOI: https://doi.org/10.1124/molpharm.120.000225
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In this issue

Molecular Pharmacology: 99 (6)
Molecular Pharmacology
Vol. 99, Issue 6
1 Jun 2021
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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