Article Figures & Data
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Data Supplement
- Supplemental Data -
Supplemental Methods
Supplemental Figure 1 - Immunocytochemical staining of cytosolic and mitochondrial localized apoaequorin.
Supplemental Figure 2 - Aequorin-mediated luminescence signal of HEK293 cells depends on the expression of CNGA3.
Supplemental Figure 3 - Comparison of fold changes obtained with CNGA3WT and CNGA3E228K after treatment with five dihydropyridines.
Supplemental Figure 4 -Graphical representation of the FCmax and the concentration necessary to reach FCmax for the compounds of the pyrazine amide and benzamide class
Supplemental Table 1 - Summary of the measured fold changes (FC) of compounds analyzed with the bioassay.
Supplemental Table 2 - Summary of compounds tested for determining structure-activity relationship of the dihydropyridine (DHP) compound class.
Supplemental Table 3 - Molecular structure of the additionally tested dihydropyridine (DHP) derivates.
- Supplemental Data -