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Molecular Pharmacology

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Research ArticleArticle

Identification of Survival Genes in Human Glioblastoma Cells Using siRNA Screening

Nikhil G Thaker, Fang Zhang, Peter R. McDonald, Tong Ying Shun, Michael D Lewen, Ian F. Pollack and John S. Lazo
Molecular Pharmacology September 28, 2009, mol.109.058024; DOI: https://doi.org/10.1124/mol.109.058024
Nikhil G Thaker
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Fang Zhang
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Peter R. McDonald
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Tong Ying Shun
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Michael D Lewen
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Ian F. Pollack
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John S. Lazo
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Additional Files

  • Data Supplement

    Files in this Data Supplement:

    • Data Supplement - Supplemental Figure legends
    • Data Supplement - Supplemental Table 6: Ranked Survival Genes.
    • Data Supplement - Supplemental Table 7: Inhibitor - Survival gene product list.
    • Data Supplement - Supplemental Table 8: siRNA sequences for targeting PSMB3, PSMB4, DDX39 and RAN.
    • Data Supplement - Supplemental Table 9: Functional classification of survival genes.
    • Data Supplement - Supplemental Figure 1: Validation of survival gene hits.
    • Data Supplement - Supplemental Figure 2: Expression of PSMB1, PSMB2, and PSMB5 in human glioma, endothelial cells and astrocytes.
    • Data Supplement - Supplemental Figure 3: Biological pathways represented by survival genes.
    • Data Supplement - Supplemental Table 1: Genes identified as reproducibly essential genes for glioma cell viability using the binning method.
    • Data Supplement - Supplemental Table 2: Genes identified as reproducibly essential genes for glioma cell viability using the MAD method.
    • Data Supplement - Suppleental Table 3: "Survival genes," present in both the binned (Table S1) and MAD (Table S2) gene lists.
    • Data Supplement - Supplemental Table 4: Survival Genes with binning and percent viability.
    • Data Supplement - Supplemental Table 5: Results from the MAD analyses of survival genes from individual experiments.
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Molecular Pharmacology: 104 (4)
Molecular Pharmacology
Vol. 104, Issue 4
1 Oct 2023
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Research ArticleArticle

Identification of Survival Genes in Human Glioblastoma Cells Using siRNA Screening

Nikhil G Thaker, Fang Zhang, Peter R. McDonald, Tong Ying Shun, Michael D Lewen, Ian F. Pollack and John S. Lazo
Molecular Pharmacology September 28, 2009, mol.109.058024; DOI: https://doi.org/10.1124/mol.109.058024

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Research ArticleArticle

Identification of Survival Genes in Human Glioblastoma Cells Using siRNA Screening

Nikhil G Thaker, Fang Zhang, Peter R. McDonald, Tong Ying Shun, Michael D Lewen, Ian F. Pollack and John S. Lazo
Molecular Pharmacology September 28, 2009, mol.109.058024; DOI: https://doi.org/10.1124/mol.109.058024
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