TAK-242 (Resatorvid), a Small Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules

Naoko Matsunaga; Noboru Tsuchimori; Tatsumi Matsumoto; Masayuki Ii

doi:10.1124/mol.110.068064

Article Information

mol.110.068064

DOI

https://doi.org/10.1124/mol.110.068064

PubMed

20881006

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0026-895X

Online ISSN

1521-0111

History

Received August 9, 2010
Revision received September 28, 2010
Accepted September 29, 2010
Published online September 29, 2010.

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The American Society for Pharmacology and Experimental Therapeutics

Author Information

Naoko Matsunaga,
Noboru Tsuchimori*,
Tatsumi Matsumoto and
Masayuki Ii

Takeda Pharmaceutical Company Limited

* Corresponding author; email: tsuchimori_noboru{at}takeda.co.jp

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