Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Shanti Diwakarla; Erik Nylander; Alfhild Gronbladh; Sudarsana Reddy Vanga; Yasmin Shamsudin Khan; Hugo Gutierrez-de-Teran; Leelee Ng; Vi Pham; Jonas Savmarker; Thomas Lundback; Annika Jenmalm-Jensen; Hanna Andersson; Karin Engen; Ulrika Rosenstrom; Mats Larhed; Johan Aqvist; Siew Yeen Chai; Mathias Hallberg

doi:10.1124/mol.115.102533

Research ArticleArticle

Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Shanti Diwakarla, Erik Nylander, Alfhild Gronbladh, Sudarsana Reddy Vanga, Yasmin Shamsudin Khan, Hugo Gutierrez-de-Teran, Leelee Ng, Vi Pham, Jonas Savmarker, Thomas Lundback, Annika Jenmalm-Jensen, Hanna Andersson, Karin Engen, Ulrika Rosenstrom, Mats Larhed, Johan Aqvist, Siew Yeen Chai and Mathias Hallberg

Molecular Pharmacology January 14, 2016, mol.115.102533; DOI: https://doi.org/10.1124/mol.115.102533

Shanti Diwakarla

1 Uppsala University;

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Erik Nylander

1 Uppsala University;

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Alfhild Gronbladh

1 Uppsala University;

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Sudarsana Reddy Vanga

1 Uppsala University;

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Yasmin Shamsudin Khan

1 Uppsala University;

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Hugo Gutierrez-de-Teran

1 Uppsala University;

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Leelee Ng

2 Monash University;

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Vi Pham

2 Monash University;

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Jonas Savmarker

1 Uppsala University;

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Thomas Lundback

3 Karolinska Institute

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Annika Jenmalm-Jensen

3 Karolinska Institute

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Hanna Andersson

1 Uppsala University;

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Karin Engen

1 Uppsala University;

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Ulrika Rosenstrom

1 Uppsala University;

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Mats Larhed

1 Uppsala University;

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Johan Aqvist

1 Uppsala University;

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Siew Yeen Chai

2 Monash University;

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Mathias Hallberg

1 Uppsala University;

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Molecular Pharmacology

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Research ArticleArticle

Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Molecular Pharmacology January 14, 2016, mol.115.102533; DOI: https://doi.org/10.1124/mol.115.102533

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Research ArticleArticle

Binding to and Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Macrocyclic Disulfides Enhances Spine Density

Molecular Pharmacology January 14, 2016, mol.115.102533; DOI: https://doi.org/10.1124/mol.115.102533

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