Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Pharmacology
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Molecular Pharmacology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Visit molpharm on Facebook
  • Follow molpharm on Twitter
  • Follow molpharm on LinkedIn
Research ArticleArticle

Generation and characterization of an Abcc1 humanized mouse model (hABCC1flx/flx) with knockout capability

Markus Krohn, Victoria Zoufal, Severin Mairinger, Thomas Wanek, Kristin Paarmann, Thomas Bruning, Ivan Eiriz, Mirjam Brackhan, Oliver Langer and Jens Pahnke
Molecular Pharmacology June 12, 2019, mol.119.115824; DOI: https://doi.org/10.1124/mol.119.115824
Markus Krohn
1 University of Oslo;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Victoria Zoufal
2 AIT
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Severin Mairinger
2 AIT
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas Wanek
2 AIT
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kristin Paarmann
1 University of Oslo;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas Bruning
1 University of Oslo;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ivan Eiriz
1 University of Oslo;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mirjam Brackhan
1 University of Oslo;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Oliver Langer
2 AIT
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jens Pahnke
1 University of Oslo;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jens Pahnke
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

Article Figures & Data

Additional Files

  • Data Supplement

    • Supplemental Data -

      Supplementary Table 1 - Genotyping primer contributions to the possible occurring genotypes.

      Supplementary Table 2 -  Actb Ct-values of analysed groups.

      Supplementary Table 3 - Western blot luminescence signals of ATP1A2 bands.

      Supplementary Figure 1 -  mRNA expression analyses.

      Supplementary Fig. 2 -  ABCC1 expression in spleen (A), kidney (B) and CP(C).

      Supplementary Fig. 3 -  Antibody clone QCRL-1 is not specific for human ABCC1.

      Supplementary Fig. 4 - Comparison of antibody clones QCRL-1 and MRPr1.

Next
Back to top

In this issue

Molecular Pharmacology: 99 (2)
Molecular Pharmacology
Vol. 99, Issue 2
1 Feb 2021
  • Table of Contents
  • About the Cover
  • Index by author
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Molecular Pharmacology article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Generation and characterization of an Abcc1 humanized mouse model (hABCC1flx/flx) with knockout capability
(Your Name) has forwarded a page to you from Molecular Pharmacology
(Your Name) thought you would be interested in this article in Molecular Pharmacology.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Generation and characterization of an Abcc1 humanized mouse model (hABCC1flx/flx) with knockout capability

Markus Krohn, Victoria Zoufal, Severin Mairinger, Thomas Wanek, Kristin Paarmann, Thomas Bruning, Ivan Eiriz, Mirjam Brackhan, Oliver Langer and Jens Pahnke
Molecular Pharmacology June 12, 2019, mol.119.115824; DOI: https://doi.org/10.1124/mol.119.115824

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Research ArticleArticle

Generation and characterization of an Abcc1 humanized mouse model (hABCC1flx/flx) with knockout capability

Markus Krohn, Victoria Zoufal, Severin Mairinger, Thomas Wanek, Kristin Paarmann, Thomas Bruning, Ivan Eiriz, Mirjam Brackhan, Oliver Langer and Jens Pahnke
Molecular Pharmacology June 12, 2019, mol.119.115824; DOI: https://doi.org/10.1124/mol.119.115824
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • GABAAR Molecular Identity in Oligodendrocytes
  • Editing TOP2α Intron-19 5′ SS Circumvents Drug Resistance
  • SerpinA3N and drug induced liver injury
Show more Article

Similar Articles

  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Molecular Pharmacology
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0111 (Online)

Copyright © 2021 by the American Society for Pharmacology and Experimental Therapeutics