Article Figures & Data
Additional Files
Data Supplement
- Supplemental Figures -
Supplementary Figure 1 - TRPA1 and TRPV3 antagonists and EGTA/RR do not elicit calcium flux in lobar HBECs.
Supplementary Figure 2 - Multiple forms of wood/biomass smoke PM induce DDIT3 and ATF3 in lobar HBECs.
Supplementary Figure 3 - (A) Low magnification confocal micrographs of lobar HBECs immunostained for TRPV3 (green), the ER biomarker calnexin (red), and nuclei (blue). The regions outlined by the white dotted line denote the expanded cell highlighted in Figure 2. (B) Immunostaining validation, probing for TRPV3 (green) and nuclei (blue) in BEAS-2B and TRPV3-overexpressing BEAS-2B (TRPV3OE) cells.
Supplementary Figure 4 - Relative contributions of TRPV3 and TRPA1 to ERS caused by selective TRPA1 and TRPV3 agonists.
Supplementary Figure 5 - Multiple forms of wood/biomass smoke PM induce TRPV3 in lobar HBECs.
Supplementary Figure 6 - Effects of A967079 and TRPV3 antagonist onTRPA1 activation by the nonelectrophilic agonist, 2,4 ditert-butylphenol inTRPA1-overexpressing HEK-293 cells.
- Supplemental Figures -