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Molecular Pharmacology

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Eribulin activates the cGAS-STING pathway via the cytoplasmic accumulation of mtDNA

Charles S. Fermaintt, Leila Takahashi-Ruiz, Huiyun Liang, Susan L. Mooberry and April L. Risinger
Molecular Pharmacology July 26, 2021, MOLPHARM-AR-2021-000297; DOI: https://doi.org/10.1124/molpharm.121.000297
Charles S. Fermaintt
1Pharmacology, University of Texas Health Science Center at San Antonio, United States
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Leila Takahashi-Ruiz
1Pharmacology, University of Texas Health Science Center at San Antonio, United States
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Huiyun Liang
2Pharmacology, UT Health San Antonio, United States
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Susan L. Mooberry
3Pharmacology, Univ. TX Health Sci Center at San Antonio, United States
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April L. Risinger
1Pharmacology, University of Texas Health Science Center at San Antonio, United States
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  • For correspondence: risingera@uthscsa.edu
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Article Information

MOLPHARM-AR-2021-000297
DOI 
https://doi.org/10.1124/molpharm.121.000297
PubMed 
34312217

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Published online July 26, 2021.

Article Versions

  • You are currently viewing an Earlier version of this article (July 26, 2021 - 14:04).
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Copyright & Usage 
© 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution CC BY License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

Author Information

  1. Charles S. Fermaintt1,
  2. Leila Takahashi-Ruiz1,
  3. Huiyun Liang2,
  4. Susan L. Mooberry3, and
  5. April L. Risinger1,*
  1. 1Pharmacology, University of Texas Health Science Center at San Antonio, United States
  2. 2Pharmacology, UT Health San Antonio, United States
  3. 3Pharmacology, Univ. TX Health Sci Center at San Antonio, United States
  1. ↵* Corresponding Author:
    April L. Risinger, Pharmacology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7764, San Antonio, Texas, 78229, United States. E-mail: risingera{at}uthscsa.edu

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Aug 20212110187
Sep 2021129080
Oct 202160391196
Nov 202145196171
Dec 202126139155
Jan 20222310780
Feb 2022167758
Mar 20221411662
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Molecular Pharmacology: 101 (6)
Molecular Pharmacology
Vol. 101, Issue 6
1 Jun 2021
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Eribulin activates cGAS-STING via mtDNA accumulation

Charles S. Fermaintt, Leila Takahashi-Ruiz, Huiyun Liang, Susan L. Mooberry and April L. Risinger
Molecular Pharmacology July 26, 2021, MOLPHARM-AR-2021-000297; DOI: https://doi.org/10.1124/molpharm.121.000297

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Eribulin activates cGAS-STING via mtDNA accumulation

Charles S. Fermaintt, Leila Takahashi-Ruiz, Huiyun Liang, Susan L. Mooberry and April L. Risinger
Molecular Pharmacology July 26, 2021, MOLPHARM-AR-2021-000297; DOI: https://doi.org/10.1124/molpharm.121.000297
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