Senolytic-mediated elimination of head and neck tumor cells induced into senescence by cisplatin

Fereshteh Ahmadinejad; Tasia Bos; Bin Hu; Erin Britt; Jennifer Koblinski; Andrew J Souers; Joel D. Leverson; Anthony C. Faber; David A. Gewirtz; Hisashi Harada

doi:10.1124/molpharm.121.000354

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Senolytic-mediated elimination of head and neck tumor cells induced into senescence by cisplatin

Fereshteh Ahmadinejad, Tasia Bos, Bin Hu, Erin Britt, Jennifer Koblinski, Andrew J Souers, Joel D. Leverson, Anthony C. Faber, David A. Gewirtz and Hisashi Harada

Molecular Pharmacology December 14, 2021, MOLPHARM-AR-2021-000354; DOI: https://doi.org/10.1124/molpharm.121.000354

Fereshteh Ahmadinejad

1Human and Molecular Genetics, Virginia Commonwealth University, United States

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Tasia Bos

2Virginia Commonwealth University, United States

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Bin Hu

2Virginia Commonwealth University, United States

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Erin Britt

2Virginia Commonwealth University, United States

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Jennifer Koblinski

2Virginia Commonwealth University, United States

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Andrew J Souers

3Abbvie, United States

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Joel D. Leverson

4AbbVie, United States

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Anthony C. Faber

2Virginia Commonwealth University, United States

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David A. Gewirtz

5Dept. of Medicine, Virginia Commonwealth University, United States

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Hisashi Harada

6Massey Cancer Center, VCU, United States

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For correspondence: hharada@vcu.edu

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Molecular Pharmacology

Vol. 101, Issue 2

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Recovery and elimination of senescent tumor cells

Fereshteh Ahmadinejad, Tasia Bos, Bin Hu, Erin Britt, Jennifer Koblinski, Andrew J Souers, Joel D. Leverson, Anthony C. Faber, David A. Gewirtz and Hisashi Harada

Molecular Pharmacology December 14, 2021, MOLPHARM-AR-2021-000354; DOI: https://doi.org/10.1124/molpharm.121.000354

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OtherArticle

Recovery and elimination of senescent tumor cells

Fereshteh Ahmadinejad, Tasia Bos, Bin Hu, Erin Britt, Jennifer Koblinski, Andrew J Souers, Joel D. Leverson, Anthony C. Faber, David A. Gewirtz and Hisashi Harada

Molecular Pharmacology December 14, 2021, MOLPHARM-AR-2021-000354; DOI: https://doi.org/10.1124/molpharm.121.000354

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