Pore opening, not voltage sensor movement, underpins the voltage-dependence of facilitation by a hERG blocker

Kazuharu Furutani; Ryotaro Kawano; Minami Ichiwara; Ryo Adachi; Colleen E Clancy; Jon T Sack; Satomi Kita

doi:10.1124/molpharm.122.000569

OtherArticle

Pore opening, not voltage sensor movement, underpins the voltage-dependence of facilitation by a hERG blocker

Kazuharu Furutani, Ryotaro Kawano, Minami Ichiwara, Ryo Adachi, Colleen E Clancy, Jon T Sack and Satomi Kita

Molecular Pharmacology August 30, 2022, MOLPHARM-AR-2022-000569; DOI: https://doi.org/10.1124/molpharm.122.000569

Kazuharu Furutani

1Department of Pharmacology, Tokushima Bunri University, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kazuharu Furutani
For correspondence: furutani@ph.bunri-u.ac.jp

Ryotaro Kawano

1Department of Pharmacology, Tokushima Bunri University, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Minami Ichiwara

1Department of Pharmacology, Tokushima Bunri University, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ryo Adachi

1Department of Pharmacology, Tokushima Bunri University, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Colleen E Clancy

2UC Davis School of Medicine, United States

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jon T Sack

2UC Davis School of Medicine, United States

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Satomi Kita

1Department of Pharmacology, Tokushima Bunri University, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
Info & Metrics
eLetters
PDF + SI
PDF

Compose eLetter

Title *

Contents

More information about text formats

Plain text

No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First Name and Middle Initial * First or given name, e.g. 'Peter'. Last Name * Your last, or family, name, e.g. 'MacMoody'. Email Address * Your email address, e.g. higgs-boson@gmail.com Occupation * Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation * Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests? *

Yes

Please describe the competing interests

Vertical Tabs

Jump to comment:

No eLetters have been published for this article.

In this issue

Molecular Pharmacology

Vol. 104, Issue 6

1 Dec 2023

Table of Contents
Table of Contents (PDF)
About the Cover
Index by author
Editorial Board (PDF)
Front Matter (PDF)

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for sharing this Molecular Pharmacology article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Pore opening, not voltage sensor movement, underpins the voltage-dependence of facilitation by a hERG blocker

Message Subject (Your Name) has forwarded a page to you from Molecular Pharmacology

Message Body (Your Name) thought you would be interested in this article in Molecular Pharmacology.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

OtherArticle

Effect of nifekalant on D540K hERG channels

Kazuharu Furutani, Ryotaro Kawano, Minami Ichiwara, Ryo Adachi, Colleen E Clancy, Jon T Sack and Satomi Kita

Molecular Pharmacology August 30, 2022, MOLPHARM-AR-2022-000569; DOI: https://doi.org/10.1124/molpharm.122.000569

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

OtherArticle

Effect of nifekalant on D540K hERG channels

Kazuharu Furutani, Ryotaro Kawano, Minami Ichiwara, Ryo Adachi, Colleen E Clancy, Jon T Sack and Satomi Kita

Molecular Pharmacology August 30, 2022, MOLPHARM-AR-2022-000569; DOI: https://doi.org/10.1124/molpharm.122.000569

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Jump to section

Article
Figures & Data
Info & Metrics
eLetters
PDF + SI
PDF

Main menu

User menu

Search

Pore opening, not voltage sensor movement, underpins the voltage-dependence of facilitation by a hERG blocker

Plain text

Vertical Tabs

Jump to comment:

In this issue

Effect of nifekalant on D540K hERG channels

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Navigate

More Information

ASPET's Other Journals