Article Figures & Data
Additional Files
Data Supplement
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Supplemental Figure 1. PREPL expression in hippocampus of aged rats.
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Data Supplement
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Supplemental Figure 2. Validation of PREPL knock-down using shRNA in Neuro2A, Neuro2A overexpressing-APP, and
HT22 cells
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Data Supplement
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Supplemental Figure 3. PREPL knockdown impairs cell proliferation.
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Data Supplement
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Supplemental Figure 7. Effect of PREPL knockdown on Tau phosphorylation levels.
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Data Supplement
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Supplemental Figure 6. Colocalization of PREPL with Rab 5, Rab 7, Rab 9, TGN38 and calnexin.
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Data Supplement
- Supplemental Table -
Supplemental Table 6. Differentially expressed proteins (DEPs) induced by PREPL KD were enriched for differentially expressed genes (DEGs) in human AD brains from published studies.
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Data Supplement
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Supplemental Table 2. Gene ontology pathways enriched in the PREPL knock-down induced DEGs.
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Data Supplement
- Supplemental Table -
Supplemental Table 3. Differentially expressed genes (DEGs) induced by PREPL KD were enriched for DEGs in human AD brains from published studies.
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Data Supplement
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Supplemental Figure 5. Western blot analysis for Calnexin, CgA, PREPL, SNAP25, VAMP2.
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Data Supplement
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Supplemental Table 4. Proteins differentially expressed in the PREPL KD samples.
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Data Supplement
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Supplemental Table 1. PREPL DEGs between knock down (KD) and wild type (WT) samples.
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Data Supplement
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Supplemental Figure 4. Western blot analysis for AP-1, PC1 and PC2.
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Data Supplement
- Supplemental Table -
Supplemental Table 5. Gene ontology pathways enriched in the PREPL knock-down induced differentially expressed proteins (DEPs).
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Data Supplement
- Supplemental Figure -
Supplemental Figure 8. PREPL mRNA analysis for identification of the most efficient ODN sequence for electrophysiology studies.
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