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Molecular Pharmacology

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Fast Forward

Molecular Pharmacology Fast Forward contains papers in manuscript form that have been accepted and published in Molecular Pharmacology but have not been copyedited and have not been assigned to an issue of the journal. Copyediting may lead to some differences between the Fast Forward version and the final version. There may also be differences in the quality of the graphics. The publication date appears below each title followed by the article's unique Digital Object Identifier (DOI).

Articles

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    The Small Molecule Antagonist KCI807 Disrupts Association of the Amino-terminal Domain of the Androgen Receptor with ELK1 by Modulating the Adjacent DNA Binding Domain
    Claire Soave, Charles Ducker, Naeyma Islam, Seongho Kim, Sally Yurgelevic, Nathan I Nicely, Luke Pardy, Yanfang Huang, Peter Shaw, Gregory Auner, Alex Dickson and Manohar Ratnam
    Molecular Pharmacology January 31, 2023, MOLPHARM-AR-2022-000589; DOI: https://doi.org/10.1124/molpharm.122.000589
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    Genetic Knockout of Fatty Acid Amide Hydrolase (FAAH) Ameliorates Cisplatin-induced Nephropathy in Mice
    Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin Poklis, Brandon Em, David A. Gewirtz, Aron H. Lichtman and Ningjun Li
    Molecular Pharmacology January 26, 2023, MOLPHARM-AR-2022-000618; DOI: https://doi.org/10.1124/molpharm.122.000618
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    A novel role of uricosuric agent benzbromarone in BK channel activation and reduction of airway smooth muscle contraction
    Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu and KeWei Wang
    Molecular Pharmacology January 20, 2023, MOLPHARM-AR-2022-000638; DOI: https://doi.org/10.1124/molpharm.122.000638
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    CRISPR/Cas9-mediated induction of relapse-specific NT5C2 and PRPS1 mutations confers thiopurine resistance as a relapsed lymphoid leukemia model
    Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, Atsushi Watanabe, Koushi Akahane, Kumiko Goi and Takeshi Inukai
    Molecular Pharmacology January 20, 2023, MOLPHARM-AR-2022-000546; DOI: https://doi.org/10.1124/molpharm.122.000546
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    Use-dependent relief of inhibition of Nav1.8 channels by A-887826
    Sooyeon Jo, Han-Xiong Bear Zhang and Bruce P. Bean
    Molecular Pharmacology January 12, 2023, MOLPHARM-AR-2022-000593; DOI: https://doi.org/10.1124/molpharm.122.000593
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    Mutual Cooperativity of Three Allosteric Sites on the Dopamine D1 Receptor
    Xushan Wang, Erik J Hembre, Paul J Goldsmith, James P Beck, Kjell A Svensson, Francis S. Willard and Robert F Bruns
    Molecular Pharmacology December 12, 2022, MOLPHARM-AR-2022-000605; DOI: https://doi.org/10.1124/molpharm.122.000605
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    The glycosylated N-terminal domain of MUC1 is involved in chemoresistance by modulating drug permeation across the plasma membrane
    Kaori Miyazaki, Hisanao Kishimoto, Hanai Kobayashi, Ayaka Suzuki, Kei Higuchi, Yoshiyuki Shirasaka and Katsuhisa Inoue
    Molecular Pharmacology December 5, 2022, MOLPHARM-AR-2022-000597; DOI: https://doi.org/10.1124/molpharm.122.000597
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    Cisplatin toxicity is mediated by direct binding to TLR4 through a mechanism that is distinct from metal allergens
    Ivan K. Domingo, Jody Groenendyk, Marek Michalak and Amit P. Bhavsar
    Molecular Pharmacology December 2, 2022, MOLPHARM-AR-2022-000595; DOI: https://doi.org/10.1124/molpharm.122.000595
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    Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in Mice Carrying the Human Pathogenic Mutation DRD2I212F
    Dayana Rodriguez-Contreras, Sheng Gong, Joesph J Lebowitz, Lev M Fedorov, Naeem Asad, Timothy M Dore, Tamara J. Phillips, Christopher P Ford, John T. Williams and Kim A. Neve
    Molecular Pharmacology December 1, 2022, MOLPHARM-AR-2022-000606; DOI: https://doi.org/10.1124/molpharm.122.000606
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    Valproic acid-induced upregulation of multidrug efflux transporter ABCG2/BCRP via PPARα-dependent mechanism in human brain endothelial cells
    Samiksha Kukal, Shivangi Bora, Neha Kanojia, Pooja Singh, Priyanka Rani Paul, Chitra Rawat, Shakti Sagar, Naveen Kumar Bhatraju, Gurpreet Kaur Grewal, Anju Singh, Shrikant Kukreti, Kapaettu Satyamoorthy and RITUSHREE KUKRETI
    Molecular Pharmacology November 22, 2022, MOLPHARM-AR-2022-000568; DOI: https://doi.org/10.1124/molpharm.122.000568

Minireview

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    Aryl hydrocarbon receptor as a therapeutical target of environmentally induced skin conditions
    Caroline de Almeida Freitas Accioli, Michelle Sabrina da Silva, Bianca Aloise Maneira Corrêa Santos and Carlos Rangel Rodrigues
    Molecular Pharmacology February 2, 2023, MOLPHARM-MR-2022-000627; DOI: https://doi.org/10.1124/molpharm.122.000627
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    "Ferroptosis, acyl starvation and breast cancer
    Rafał Bobiński, Mieczysław Dutka, Monika Pizon, Wioletta Waksmańska and Anna Pielesz
    Molecular Pharmacology December 8, 2022, MOLPHARM-MR-2022-000607; DOI: https://doi.org/10.1124/molpharm.122.000607
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    The Common LncRNAs of Neuroinflammation-Related Diseases
    Meixing Zeng, Ting Zhang, Yan Lin, Yongluan Lin and Zhuomin Wu
    Molecular Pharmacology December 1, 2022, MOLPHARM-MR-2022-000530; DOI: https://doi.org/10.1124/molpharm.122.000530

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