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Molecular Pharmacology

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Latest Articles

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    Dual-Activity Fluoroquinolone-Transportan 10 Conjugates offer alternative Leukemia therapy during Hematopoietic Cell Transplantation
    Jan Jakub Lica, Mateusz Heldt, Miłosz Wieczór, Paweł Chodnicki, Natalia Ptaszyńska, Natalia Maciejewska, Anna Łęgowska, Wioletta Brankiewicz, Katarzyna Gucwa, Anna Stupak, Bhaskar Pradhan, Agata Gitlin-Domagalska, Dawid Dębowski, Sławomir Milewski, Maria Bieniaszewska, Grzegorz Jan Grabe, Andrzej Hellmann and Krzysztof Rolka
    Molecular Pharmacology November 17, 2023, MOLPHARM-AR-2023-000735; DOI: https://doi.org/10.1124/molpharm.123.000735
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    Pharmacological characterization of the zebrafish (Danio rerio) histamine H1 receptor reveals the involvement of the second extracellular loop in the binding of histamine
    Daniel A McNaught-Flores, Albert J Kooistra, Yu-Chia Chen, Jose-Antonio Arias-Montano, Pertti Panula and Rob Leurs
    Molecular Pharmacology November 17, 2023, MOLPHARM-AR-2023-000741; DOI: https://doi.org/10.1124/molpharm.123.000741
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    Substituted Cysteine Modification and Protection with n-Alkyl-MTS Reagents Quantifies Steric Changes Induced by a Mutation in Anesthetic Binding Sites on GABA Type A Receptors
    Kieran Bhave and Stuart A. Forman
    Molecular Pharmacology December 2023, 104 (6) 266-274; DOI: https://doi.org/10.1124/molpharm.123.000719
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    Molecular Mechanisms of Organic Anion Transporting Polypeptide–Mediated Organic Anion Clearance at the Blood–Cerebrospinal Fluid Barrier
    Austin Sun, Bruno Hagenbuch, Edward J. Kelly and Joanne Wang
    Molecular Pharmacology December 2023, 104 (6) 255-265; DOI: https://doi.org/10.1124/molpharm.123.000703
  • Targeting Cyclophilin A and CD147 to Inhibit Replication of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and SARS-CoV-2–Induced Inflammation
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    Targeting Cyclophilin A and CD147 to Inhibit Replication of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and SARS-CoV-2–Induced Inflammation
    Fan Yang, Chenglong Liu, Pengyuan Li, Aihua Wu, Yue Ma-Lauer, Hao Zhang, Zhuang Su, Wei Lu, Albrecht von Brunn and Di Zhu
    Molecular Pharmacology December 2023, 104 (6) 239-254; DOI: https://doi.org/10.1124/molpharm.122.000587
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    Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca2+ Monitoring
    Mai Takenaka, Masami Kodama, Takashi Murayama, Mari Ishigami-Yuasa, Shuichi Mori, Ryosuke Ishida, Junji Suzuki, Kazunori Kanemaru, Masami Sugihara, Masamitsu Iino, Aya Miura, Hajime Nishio, Sachio Morimoto, Hiroyuki Kagechika, Takashi Sakurai and Nagomi Kurebayashi
    Molecular Pharmacology December 2023, 104 (6) 275-286; DOI: https://doi.org/10.1124/molpharm.123.000720
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    Passive Immunotherapies Targeting Amyloid-β in Alzheimer's Disease: A Quantitative Systems Pharmacology Perspective
    Milica Markovic, Jelica Milošević, Weirong Wang and Yanguang Cao
    Molecular Pharmacology October 31, 2023, MOLPHARM-MR-2023-000726; DOI: https://doi.org/10.1124/molpharm.123.000726
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    A 19F-qNMR-Guided Mathematical Model for G Protein-Coupled Receptor Signaling
    Jesús Giraldo, Jesper J Madsen, Xudong Wang, Lei Wang, Cheng Zhang and Libin Ye
    Molecular Pharmacology October 31, 2023, MOLPHARM-AR-2023-000754; DOI: https://doi.org/10.1124/molpharm.123.000754
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    Synergy between interleukin-1β, interferon-γ and glucocorticoids to induce TLR2 expression involves NF-κB, STAT1 and GR
    Akanksha Bansal, Cora Kooi, Keerthana Kalyanaraman, Sachman Gill, Andrew Thorne, Priyanka Chandramohan, Amandah Necker-Brown, Mahmoud M Mostafa, Arya Milani, Richard Leigh and Robert Newton
    Molecular Pharmacology October 20, 2023, MOLPHARM-AR-2023-000740; DOI: https://doi.org/10.1124/molpharm.123.000740
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    St. John's wort formulations induce rat CYP3A23-3A1 independent of their hyperforin content
    Anima M. Schäfer, Marta A. Rysz, Julia Schädeli, Michelle Hübscher, Haleh Khosravi, Michelle Fehr, Isabell Seibert, Olivier Potterat, Martin Smieško and Henriette E. Meyer zu Schwabedissen
    Molecular Pharmacology October 20, 2023, MOLPHARM-AR-2023-000725; DOI: https://doi.org/10.1124/molpharm.123.000725

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