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Identification of Celecoxib targeted proteins using label-free thermal proteome profiling on rat hippocampus
Elham Gholizadeh, Reza Karbalaei, Ali Khaleghian, Mona Salimi, Kambiz Gilany, Rabah Soliymani, Ziaurrehman Tanoli, Hassan Rezadoost, Marc Baumann, Mohieddin Jafari and Jing Tang

Molecular Pharmacology February 25, 2021, MOLPHARM-AR-2020-000210; DOI: https://doi.org/10.1124/molpharm.120.000210
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CRISPR/Cas9 Genome Editing of the Human Topoisomerase IIα Intron 19 5′ Splice Site Circumvents Etoposide Resistance in Human Leukemia K562 Cells
Victor A. Hernandez, Jessika Carvajal-Moreno, Jonathan L. Papa, Nicholas Shkolnikov, Junan Li, Hatice Gulcin Ozer, Jack C. Yalowich and Terry S. Elton

Molecular Pharmacology March 2021, 99 (3) 226-241; DOI: https://doi.org/10.1124/molpharm.120.000173
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Biased Effect of Cardiotonic Steroids on Na/K-ATPase–Mediated Signal Transduction
Yunhui Xu, Pauline Marck, Minqi Huang, Jeffrey X. Xie, Tong Wang, Joseph I. Shapiro, Liquan Cai, Feng Feng and Zijian Xie

Molecular Pharmacology March 2021, 99 (3) 217-225; DOI: https://doi.org/10.1124/molpharm.120.000101
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Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias
Angela Arsova, Thor C. Møller, Shane D. Hellyer, Line Vedel, Simon R. Foster, Jakob L. Hansen, Hans Bräuner-Osborne and Karen J. Gregory

Molecular Pharmacology February 18, 2021, MOLPHARM-AR-2020-000185; DOI: https://doi.org/10.1124/molpharm.120.000185
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Transcriptome-Level Interactions between Budesonide and Formoterol Provide Insight into the Mechanism of Action of Inhaled Corticosteroid/Long-Acting β₂-Adrenoceptor Agonist Combination Therapy in Asthma
Mahmoud M. Mostafa, Christopher F. Rider, N. Dulmini Wathugala, Richard Leigh, Mark A. Giembycz and Robert Newton

Molecular Pharmacology March 2021, 99 (3) 197-216; DOI: https://doi.org/10.1124/molpharm.120.000146
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Title: Phosphoproteomic Analysis as an Approach for Understanding Molecular Mechanisms of cAMP-dependent Actions
Joseph A. Beavo, Martin Golkowski, Masami Shimizu-Albergine, Michael-Claude Beltejar, Karin E. Bornfeldt and Shao-En Ong

Molecular Pharmacology February 11, 2021, MOLPHARM-MR-2020-000197; DOI: https://doi.org/10.1124/molpharm.120.000197
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Elevated cAMP protects against diclofenac-induced toxicity in primary rat hepatocytes: a protective effect mediated by EPACs
Fabio Alejandro Aguilar Mora, Nshunge Musheshe, Asmaa Oun, Manon Buist-Homan, Frank Lezoualc'h, Xiaodong Cheng, Martina Schmidt and Han Moshage

Molecular Pharmacology February 11, 2021, MOLPHARM-AR-2020-000217; DOI: https://doi.org/10.1124/molpharm.120.000217
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Nelfinavir and Its Active Metabolite M8 Are Partial Agonists and Competitive Antagonists of the Human Pregnane X Receptor
Oliver Burk, Thales Kronenberger, Oliver Keminer, Serene M. L. Lee, Tobias S. Schiergens, Matthias Schwab and Björn Windshügel

Molecular Pharmacology March 2021, 99 (3) 184-196; DOI: https://doi.org/10.1124/molpharm.120.000116
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Short-Term Acyl-CoA:Cholesterol Acyltransferase Inhibition, Combined with Apoprotein A1 Overexpression, Promotes Atherosclerosis Inflammation Resolution in Mice
Jaume Amengual, Yoscar Ogando, Cyrus Nikain, Alexandra Quezada, Kun Qian, Tomas Vaisar and Edward A. Fisher

Molecular Pharmacology March 2021, 99 (3) 175-183; DOI: https://doi.org/10.1124/molpharm.120.000108
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Chronic exposure to SCO-267, an allosteric GPR40 full agonist, is effective in improving glycemic control in rats
Ryokichi Koyama, Mitsugi Ookawara, Masanori Watanabe and Yusuke Moritoh

Molecular Pharmacology February 5, 2021, MOLPHARM-AR-2020-000168; DOI: https://doi.org/10.1124/molpharm.120.000168

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