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Genetic Knockout of Fatty Acid Amide Hydrolase (FAAH) Ameliorates Cisplatin-induced Nephropathy in Mice
Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin Poklis, Brandon Em, David A. Gewirtz, Aron H. Lichtman and Ningjun Li

Molecular Pharmacology January 26, 2023, MOLPHARM-AR-2022-000618; DOI: https://doi.org/10.1124/molpharm.122.000618
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A Complete Endocannabinoid Signaling System Modulates Synaptic Transmission between Human Induced Pluripotent Stem Cell–Derived Neurons
Melissa J. Asher, Hannah M. McMullan, Ao Dong, Yulong Li and Stanley A. Thayer

Molecular Pharmacology February 2023, 103 (2) 100-112; DOI: https://doi.org/10.1124/molpharm.122.000555
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A novel role of uricosuric agent benzbromarone in BK channel activation and reduction of airway smooth muscle contraction
Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu and KeWei Wang

Molecular Pharmacology January 20, 2023, MOLPHARM-AR-2022-000638; DOI: https://doi.org/10.1124/molpharm.122.000638
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CRISPR/Cas9-mediated induction of relapse-specific NT5C2 and PRPS1 mutations confers thiopurine resistance as a relapsed lymphoid leukemia model
Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, Atsushi Watanabe, Koushi Akahane, Kumiko Goi and Takeshi Inukai

Molecular Pharmacology January 20, 2023, MOLPHARM-AR-2022-000546; DOI: https://doi.org/10.1124/molpharm.122.000546
Open Access
Multiplex G Protein–Coupled Receptor Screen Reveals Reliably Acting Agonists and a Gq-Phospholipase C Coupling Mode of GPR30/GPER1
Nicole Urban, Marion Leonhardt and Michael Schaefer

Molecular Pharmacology February 2023, 103 (2) 48-62; DOI: https://doi.org/10.1124/molpharm.122.000580
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New Leadership and Ideas for Molecular Pharmacology
Molecular Pharmacology February 2023, 103 (2) 45-47; DOI: https://doi.org/10.1124/molpharm.122.000660
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The Isoleucine at Position 118 in Transmembrane 2 Is Responsible for the Selectivity of Xamoterol, Nebivolol, and ICI89406 for the Human β1-Adrenoceptor
Victor Jun Yu Lim, Richard G. W. Proudman, Stefania Monteleone, Peter Kolb and Jillian G. Baker

Molecular Pharmacology February 2023, 103 (2) 89-99; DOI: https://doi.org/10.1124/molpharm.122.000583
Open Access
Differences in Sustained Cellular Effects of MET inhibitors Are Driven by Prolonged Target Engagement and Lysosomal Retention
Nina Berges, Jan Henrik Klug, Anna Eicher, Jennifer Loehr, Daniel Schwarz, Joerg Bomke, Birgitta Leuthner, Dominique Perrin and Oliver Schadt

Molecular Pharmacology February 2023, 103 (2) 77-88; DOI: https://doi.org/10.1124/molpharm.122.000590
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Insights Into the Differential Desensitization of α4β2 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors
Roger L. Papke and Clare Stokes

Molecular Pharmacology February 2023, 103 (2) 63-76; DOI: https://doi.org/10.1124/molpharm.122.000591
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Use-dependent relief of inhibition of Nav1.8 channels by A-887826
Sooyeon Jo, Han-Xiong Bear Zhang and Bruce P. Bean

Molecular Pharmacology January 12, 2023, MOLPHARM-AR-2022-000593; DOI: https://doi.org/10.1124/molpharm.122.000593

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