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Molecular Pharmacology

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Latest Articles

  • Open Access
    Novel Small Molecule Fibroblast Growth Factor 23 Inhibitors Increase Serum Phosphate and Improve Skeletal Abnormalities in Hyp Mice
    Zhousheng Xiao, Jiawang Liu, Shih-Hsien Liu, Loukas Petridis, Chun Cai, Li Cao, Guangwei Wang, Ai Lin Chin, Jacob W. Cleveland, Munachi O. Ikedionwu, Jesse D. Carrick, Jeremy C. Smith and Leigh Darryl Quarles
    Molecular Pharmacology June 2021, 101 (6) 408-421; DOI: https://doi.org/10.1124/molpharm.121.000471
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    Coassembly of Warm Temperature–Sensitive Transient Receptor Potential Vanilloid (TRPV) 3 and TRPV4 Channel Complexes with Distinct Functional Properties
    Fang Hu, Xu Cao, Canyang Niu and KeWei Wang
    Molecular Pharmacology June 2022, 101 (6) 390-399; DOI: https://doi.org/10.1124/molpharm.121.000370
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    Secretin Amino-Terminal Structure-Activity Relationships and Complementary Mutagenesis at the Site of Docking to the Secretin Receptor
    Juliana E. Milburn, Kaleeckal G. Harikumar, Sarah J. Piper, Sweta Raval, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton and Laurence J. Miller
    Molecular Pharmacology June 2022, 101 (6) 400-407; DOI: https://doi.org/10.1124/molpharm.122.000502
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    Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake
    Vusumuzi N. Hove, Kenneth Anderson, Elizabeth R. Hayden, Kyle Z. Pasquariello, Alice A. Gibson, Shichen Shen, Jun Qu, Yan Jin, Jeffrey C. Miecznikowski, Shuiying Hu and Jason A. Sprowl
    Molecular Pharmacology June 2022, 101 (6) 381-389; DOI: https://doi.org/10.1124/molpharm.121.000287
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    Calcium cycling as a mediator of thermogenic metabolism in adipose tissue
    Adrienne R Guarnieri, Tyler W Benson and Michael Tranter
    Molecular Pharmacology May 3, 2022, MOLPHARM-MR-2021-000465; DOI: https://doi.org/10.1124/molpharm.121.000465
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    Discovery of novel activators of large-conductance calcium-activated potassium channels for the treatment of cerebellar ataxia
    Sharan R. Srinivasan, Haoran Huang, Wei-Chih Chang, Joshua A. Nasburg, Hai M. Nguyen, Tim Strassmaier, Heike Wulff and Vikram G. Shakkottai
    Molecular Pharmacology April 30, 2022, MOLPHARM-AR-2021-000478; DOI: https://doi.org/10.1124/molpharm.121.000478
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    The Synthetic Cannabinoid WIN55,212-2 Can Disrupt the Golgi Apparatus Independent of Cannabinoid Receptor-1
    Joshua Lott, Emily M. Jutkiewicz and Manojkumar A. Puthenveedu
    Molecular Pharmacology May 2022, 101 (5) 371-380; DOI: https://doi.org/10.1124/molpharm.121.000377
  • Nuclear Ceramide Is Associated with Ataxia Telangiectasia Mutated Activation in the Neocarzinostatin-Induced Apoptosis of Lymphoblastoid Cells
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    Nuclear Ceramide Is Associated with Ataxia Telangiectasia Mutated Activation in the Neocarzinostatin-Induced Apoptosis of Lymphoblastoid Cells
    Jun Fujita, Makoto Taniguchi, Chieko Hashizume, Yoshibumi Ueda, Shota Sakai, Tadakazu Kondo, Mayumi Hashimoto-Nishimura, Kentaro Hanada, Takeo Kosaka and Toshiro Okazaki
    Molecular Pharmacology May 2022, 101 (5) 322-333; DOI: https://doi.org/10.1124/molpharm.121.000379
  • Open Access
    Influence of the TARP γ8-Selective Negative Allosteric Modulator JNJ-55511118 on AMPA Receptor Gating and Channel Conductance
    Ian D. Coombs, Craig A. Sexton, Stuart G. Cull-Candy and Mark Farrant
    Molecular Pharmacology May 2022, 101 (5) 343-356; DOI: https://doi.org/10.1124/molpharm.121.000473
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    Serotonin-Mediated Activation of Serotonin Receptor Type 1 Oppositely Modulates Voltage-Gated Calcium Channel Currents in Rat Sensory Neurons Innervating Hindlimb Muscle
    Laura Anselmi, Joyce S. Kim, Marc P. Kaufman, Shouhao Zhou and Victor Ruiz-Velasco
    Molecular Pharmacology May 2022, 101 (5) 309-321; DOI: https://doi.org/10.1124/molpharm.121.000419

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