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Molecular Pharmacology

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Latest Articles

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    Genetic Knockout of Fatty Acid Amide Hydrolase (FAAH) Ameliorates Cisplatin-induced Nephropathy in Mice
    Chaoling Chen, Weili Wang, Marissa Raymond, Fereshteh Ahmadinejad, Justin Poklis, Brandon Em, David A. Gewirtz, Aron H. Lichtman and Ningjun Li
    Molecular Pharmacology January 26, 2023, MOLPHARM-AR-2022-000618; DOI: https://doi.org/10.1124/molpharm.122.000618
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    A Complete Endocannabinoid Signaling System Modulates Synaptic Transmission between Human Induced Pluripotent Stem Cell–Derived Neurons
    Melissa J. Asher, Hannah M. McMullan, Ao Dong, Yulong Li and Stanley A. Thayer
    Molecular Pharmacology February 2023, 103 (2) 100-112; DOI: https://doi.org/10.1124/molpharm.122.000555
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    A novel role of uricosuric agent benzbromarone in BK channel activation and reduction of airway smooth muscle contraction
    Jian Gao, Hao Yin, Yanqun Dong, Xintong Wang, Yani Liu and KeWei Wang
    Molecular Pharmacology January 20, 2023, MOLPHARM-AR-2022-000638; DOI: https://doi.org/10.1124/molpharm.122.000638
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    CRISPR/Cas9-mediated induction of relapse-specific NT5C2 and PRPS1 mutations confers thiopurine resistance as a relapsed lymphoid leukemia model
    Thao Thu Thi Nguyen, Yoichi Tanaka, Masashi Sanada, Masumi Hosaka, Minori Tamai, Keiko Kagami, Chiaki Komatsu, Shinpei Somazu, Daisuke Harama, Shin Kasai, Atsushi Watanabe, Koushi Akahane, Kumiko Goi and Takeshi Inukai
    Molecular Pharmacology January 20, 2023, MOLPHARM-AR-2022-000546; DOI: https://doi.org/10.1124/molpharm.122.000546
  • Open Access
    Multiplex G Protein–Coupled Receptor Screen Reveals Reliably Acting Agonists and a Gq-Phospholipase C Coupling Mode of GPR30/GPER1
    Nicole Urban, Marion Leonhardt and Michael Schaefer
    Molecular Pharmacology February 2023, 103 (2) 48-62; DOI: https://doi.org/10.1124/molpharm.122.000580
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    New Leadership and Ideas for Molecular Pharmacology
    Molecular Pharmacology February 2023, 103 (2) 45-47; DOI: https://doi.org/10.1124/molpharm.122.000660
  • The Isoleucine at Position 118 in Transmembrane 2 Is Responsible for the Selectivity of Xamoterol, Nebivolol, and ICI89406 for the Human <em>β</em>1-Adrenoceptor
    Open Access
    The Isoleucine at Position 118 in Transmembrane 2 Is Responsible for the Selectivity of Xamoterol, Nebivolol, and ICI89406 for the Human β1-Adrenoceptor
    Victor Jun Yu Lim, Richard G. W. Proudman, Stefania Monteleone, Peter Kolb and Jillian G. Baker
    Molecular Pharmacology February 2023, 103 (2) 89-99; DOI: https://doi.org/10.1124/molpharm.122.000583
  • Open Access
    Differences in Sustained Cellular Effects of MET inhibitors Are Driven by Prolonged Target Engagement and Lysosomal Retention
    Nina Berges, Jan Henrik Klug, Anna Eicher, Jennifer Loehr, Daniel Schwarz, Joerg Bomke, Birgitta Leuthner, Dominique Perrin and Oliver Schadt
    Molecular Pharmacology February 2023, 103 (2) 77-88; DOI: https://doi.org/10.1124/molpharm.122.000590
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    Insights Into the Differential Desensitization of α4β2 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors
    Roger L. Papke and Clare Stokes
    Molecular Pharmacology February 2023, 103 (2) 63-76; DOI: https://doi.org/10.1124/molpharm.122.000591
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    Use-dependent relief of inhibition of Nav1.8 channels by A-887826
    Sooyeon Jo, Han-Xiong Bear Zhang and Bruce P. Bean
    Molecular Pharmacology January 12, 2023, MOLPHARM-AR-2022-000593; DOI: https://doi.org/10.1124/molpharm.122.000593

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