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The Emerging Role of Neuronal Organoid Models in Drug Discovery: Potential Applications and Hurdles to Implementation
Laura A Struzyna and Marla L Watt

Molecular Pharmacology February 5, 2021, MOLPHARM-MR-2020-000142; DOI: https://doi.org/10.1124/molpharm.120.000142
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Arrestin-dependent and -independent internalization of GPCRs - methods, mechanisms and implications on cell signaling
Ee Von Moo, Jeffrey R. van Senten, Hans Bräuner-Osborne and Thor C. Møller

Molecular Pharmacology January 20, 2021, MOLPHARM-MR-2020-000192; DOI: https://doi.org/10.1124/molpharm.120.000192
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Predicting Drug Interactions with Human Equilibrative Nucleoside Transporters 1 and 2 Using Functional Knockout Cell Lines and Bayesian Modeling
Siennah R. Miller, Xiaohong Zhang, Raymond K. Hau, Joseph L. Jilek, Erin Q. Jennings, James J. Galligan, Daniel H. Foil, Kimberley M. Zorn, Sean Ekins, Stephen H. Wright and Nathan J. Cherrington

Molecular Pharmacology February 2021, 99 (2) 147-162; DOI: https://doi.org/10.1124/molpharm.120.000169
Open Access
Insights into the Structure-Activity Relationship of Glycosides as Positive Allosteric Modulators Acting on P2X7 Receptors
Waraporn Piyasirananda, Andrew Beekman, A. Ganesan, Stefan Bidula and Leanne Stokes

Molecular Pharmacology February 2021, 99 (2) 163-174; DOI: https://doi.org/10.1124/molpharm.120.000129
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GABA_A Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties
Rainald Pablo Ordaz, Edith Garay, Agenor Limon, Alberto Pérez-Samartín, María Victoria Sánchez-Gómez, Leticia Robles-Martínez, Abraham Cisneros-Mejorado, Carlos Matute and Rogelio O. Arellano

Molecular Pharmacology February 2021, 99 (2) 133-146; DOI: https://doi.org/10.1124/molpharm.120.000091
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A potential role for SerpinA3N in acetaminophen-induced hepatotoxicity
Melanie Tran, Jianguo Wu, Li Wang and Dong-Ju Shin

Molecular Pharmacology January 12, 2021, MOLPHARM-AR-2020-000117; DOI: https://doi.org/10.1124/molpharm.120.000117
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Mechanism-based Inactivation of Cytochrome P450 3A4 by Benzbromarone
Lloyd Wei Tat Tang, Ravi Kumar Verma, Hao Fan and Eric Chun Yong Chan

Molecular Pharmacology January 12, 2021, MOLPHARM-AR-2020-000086; DOI: https://doi.org/10.1124/molpharm.120.000086
Open Access
Distinct Regulation of Cardiac Fibroblast Proliferation and Transdifferentiation by Classical and Novel Protein Kinase C Isoforms: Possible Implications for New Antifibrotic Therapies
S. Tuuli Karhu, Heikki Ruskoaho and Virpi Talman

Molecular Pharmacology February 2021, 99 (2) 104-113; DOI: https://doi.org/10.1124/molpharm.120.000094
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Molecular Mechanisms for the Inflammation-Resolving Actions of Lenabasum
Sumner Burstein

Molecular Pharmacology February 2021, 99 (2) 125-132; DOI: https://doi.org/10.1124/molpharm.120.000083
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Macrophage-Inducible C-Type Lectin Signaling Exacerbates Acetaminophen-Induced Liver Injury by Promoting Kupffer Cell Activation in Mice
Jing Zhao, Jong-Won Kim, Zixiong Zhou, Jing Qi, Weishun Tian, Chae Woong Lim, Kang Min Han and Bumseok Kim

Molecular Pharmacology February 2021, 99 (2) 92-103; DOI: https://doi.org/10.1124/molpharm.120.000043

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