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The intracellular N-terminus domain of the acid-sensing ion channel 1a participates in channel opening and membrane expression
Wen Li, Xiaomu Wang, Xiandong Meng and Dong Wei

Molecular Pharmacology June 1, 2021, MOLPHARM-AR-2020-000153; DOI: https://doi.org/10.1124/molpharm.120.000153
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Commentary on "Novel Interaction of the Dopamine D2 Receptor and the Ca²⁺ Binding Protein S100B: Role in D2 Receptor Function"
Hun-Joo Lee, Dayana Rodriguez-Contreras and Kim A. Neve

Molecular Pharmacology May 27, 2021, MOLPHARM-COM-2021-000284; DOI: https://doi.org/10.1124/molpharm.121.000284
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Ethnic-Related Sodium Voltage-Gated Channel α Subunit 5 Polymorphisms Shape the In Vitro Pharmacological Action of Amiodarone upon Na_v1.5
Julliane Vasconcelos Joviano-Santos, Artur Santos-Miranda, Jaqueline Oliveira Sarmento and Danilo Roman-Campos

Molecular Pharmacology June 2021, 99 (6) 448-459; DOI: https://doi.org/10.1124/molpharm.120.000176
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TP53 null mutations identify lung cancer cell lines with highest sensitivity to the non-taxane microtubule inhibitor, eribulin
Trista K. Hinz, Roshni Kalkur, Jonathan Rabinovitch, Wyatt Hinkle and Lynn E. Heasley

Molecular Pharmacology May 24, 2021, MOLPHARM-AR-2021-000254; DOI: https://doi.org/10.1124/molpharm.121.000254
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ABIN-1 in the brain alleviated opioid tolerance through its action on β-arrestin2
Yixin Zhang, Peilan Zhou, Fengfeng Lu, Ruibin Su and Zehui Gong

Molecular Pharmacology May 24, 2021, MOLPHARM-AR-2020-000211; DOI: https://doi.org/10.1124/molpharm.120.000211
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TGF-β 1 Increases Expression of Contractile Genes in Human Pulmonary Arterial Smooth Muscle Cells by Potentiating Sphingosine-1-Phosphate Signaling
Yajing Ji, Erika M. Lisabeth and Richard R. Neubig

Molecular Pharmacology May 24, 2021, MOLPHARM-AR-2020-000019; DOI: https://doi.org/10.1124/molpharm.120.000019
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Antidepressants produce persistent Gα_s associated signaling changes in lipid rafts following drug withdrawal
Nicolas B. Senese and Mark M. Rasenick

Molecular Pharmacology May 19, 2021, MOLPHARM-AR-2020-000226; DOI: https://doi.org/10.1124/molpharm.120.000226
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Inhibition of Human Uracil DNA Glycosylase Sensitizes a Large Fraction of Colorectal Cancer Cells to 5-Fluorodeoxyuridine and Raltitrexed but Not Fluorouracil
Eric S. Christenson, Anthony Gizzi, Junru Cui, Matthew Egleston, Kyle J. Seamon, Michael DePasquale, Benjamin Orris, Ben H. Park and James T. Stivers

Molecular Pharmacology June 2021, 99 (6) 412-425; DOI: https://doi.org/10.1124/molpharm.120.000191
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Novel Human-Derived RET Fusion NSCLC Cell Lines Have Heterogeneous Responses to RET Inhibitors and Differential Regulation of Downstream Signaling
Laura Schubert, Anh T. Le, Adriana Estrada-Bernal, Andrea E. Doak, Minjae Yoo, Sarah E. Ferrara, Andrew Goodspeed, Fumi Kinose, Uwe Rix, Aik-Choon Tan and Robert C. Doebele

Molecular Pharmacology June 2021, 99 (6) 435-447; DOI: https://doi.org/10.1124/molpharm.120.000207
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Substituted Cysteine Modification and Protection with n-Alkyl- Methanethiosulfonate Reagents Yields a Precise Estimate of the Distance between Etomidate and a Residue in Activated GABA Type A Receptors
Ryan J. Fantasia, Anahita Nourmahnad, Elizabeth Halpin and Stuart A. Forman

Molecular Pharmacology June 2021, 99 (6) 426-434; DOI: https://doi.org/10.1124/molpharm.120.000224

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