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N-terminal targeting of Regulator of G Protein Signaling Protein 2 for F-box Only Protein 44-mediated proteasomal degradation
Harrison J. McNabb, Stephanie Gonzalez, Christine S. Muli and Benita Sjögren

Molecular Pharmacology October 2, 2020, MOLPHARM-AR-2020-000061; DOI: https://doi.org/10.1124/molpharm.120.000061
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Structure of the complex of an iminopyridinedione PTP4A3 phosphatase inhibitor with human serum albumin
Mateusz P. Czub, Adam M. Boulton, Ettore J. Rastelli, Nikhil R. Tasker, Taber S. Maskrey, Isabella K. Blanco, Kelley E. McQueeney, John H. Bushweller, Wladek Minor, Peter Wipf, Elizabeth R. Sharlow and John S. Lazo

Molecular Pharmacology September 25, 2020, MOLPHARM-AR-2020-000131; DOI: https://doi.org/10.1124/molpharm.120.000131
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Reduced activation of the synaptic-type GABA_Areceptor following prolonged exposure to low concentrations of agonists: relationship between tonic activity and desensitization
Spencer R. Pierce, Allison L. Germann, Alex S. Evers, Joseph Henry Steinbach and Gustav Akk

Molecular Pharmacology September 25, 2020, MOLPHARM-AC-2020-000088; DOI: https://doi.org/10.1124/molpharm.120.000088
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Emerging roles for Regulator of G Protein Signaling 2 in (patho)physiology
Harrison J. McNabb, Qian Zhang and Benita Sjögren

Molecular Pharmacology September 23, 2020, MOLPHARM-MR-2020-000111; DOI: https://doi.org/10.1124/molpharm.120.000111
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Correction to “Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer”
Molecular Pharmacology October 2020, 98 (4) 528; DOI: https://doi.org/10.1124/molpharm.120.000054err
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A Truncated Six Transmembrane Splice Variant MOR-1G Enhances Expression of the Full-Length Seven Transmembrane μ-Opioid Receptor through Heterodimerization
Tiffany Zhang, Jin Xu and Ying-Xian Pan

Molecular Pharmacology October 2020, 98 (4) 518-527; DOI: https://doi.org/10.1124/mol.120.119453
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Intrinsic Efficacy of Opioid Ligands and Its Importance for Apparent Bias, Operational Analysis, and Therapeutic Window
Alexander Gillis, Varun Sreenivasan and Macdonald J. Christie

Molecular Pharmacology October 2020, 98 (4) 410-424; DOI: https://doi.org/10.1124/mol.119.119214
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Bidirectional Relationship between Opioids and Disrupted Sleep: Putative Mechanisms
D. Eacret, S.C. Veasey and J.A. Blendy

Molecular Pharmacology October 2020, 98 (4) 445-453; DOI: https://doi.org/10.1124/mol.119.119107
Open Access
Atomic-Level Characterization of the Methadone-Stabilized Active Conformation of µ-Opioid Receptor
Abhijeet Kapoor, Davide Provasi and Marta Filizola

Molecular Pharmacology October 2020, 98 (4) 475-486; DOI: https://doi.org/10.1124/mol.119.119339
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Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gαz as Shown with Bioluminescence Resonance Energy Transfer
Miriam E. Barnett, Brian I. Knapp and Jean M. Bidlack

Molecular Pharmacology October 2020, 98 (4) 462-474; DOI: https://doi.org/10.1124/mol.120.119404

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