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Physiologic Targets and Modes of Action for CBL0137, a Lead for Human African Trypanosomiasis Drug Development
Carlos E. Sanz-Rodríguez, Benjamin Hoffman, Paul J. Guyett, Andrei Purmal, Baljinder Singh, Michael P. Pollastri and Kojo Mensa-Wilmot

Molecular Pharmacology July 2022, 102 (1) 1-16; DOI: https://doi.org/10.1124/molpharm.121.000430
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GPR83 Engages Endogenous Peptides from Two Distinct Precursors to Elicit Differential Signaling
Seshat M. Mack, Ivone Gomes, Amanda K. Fakira, Mariana Lemos Duarte, Achla Gupta, Lloyd Fricker and Lakshmi A. Devi

Molecular Pharmacology July 2022, 102 (1) 29-38; DOI: https://doi.org/10.1124/molpharm.122.000487
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Sex Differences in Cardiovascular Impact of Early Metabolic Impairment: Interplay between Dysbiosis and Adipose Inflammation
Haneen S. Dwaib, Ibrahim AlZaim, Ghina Ajouz, Ali H. Eid and Ahmed El-Yazbi

Molecular Pharmacology July 2022, 102 (1) 60-79; DOI: https://doi.org/10.1124/molpharm.121.000338
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The Heartwarming Effect of Brown Adipose Tissue
Kelsey M. Pinckard and Kristin I. Stanford

Molecular Pharmacology July 2022, 102 (1) 39-50; DOI: https://doi.org/10.1124/molpharm.121.000328
Open Access
Novel Small Molecule Fibroblast Growth Factor 23 Inhibitors Increase Serum Phosphate and Improve Skeletal Abnormalities in Hyp Mice
Zhousheng Xiao, Jiawang Liu, Shih-Hsien Liu, Loukas Petridis, Chun Cai, Li Cao, Guangwei Wang, Ai Lin Chin, Jacob W. Cleveland, Munachi O. Ikedionwu, Jesse D. Carrick, Jeremy C. Smith and Leigh Darryl Quarles

Molecular Pharmacology June 2022, 101 (6) 408-421; DOI: https://doi.org/10.1124/molpharm.121.000471
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Coassembly of Warm Temperature–Sensitive Transient Receptor Potential Vanilloid (TRPV) 3 and TRPV4 Channel Complexes with Distinct Functional Properties
Fang Hu, Xu Cao, Canyang Niu and KeWei Wang

Molecular Pharmacology June 2022, 101 (6) 390-399; DOI: https://doi.org/10.1124/molpharm.121.000370
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Secretin Amino-Terminal Structure-Activity Relationships and Complementary Mutagenesis at the Site of Docking to the Secretin Receptor
Juliana E. Milburn, Kaleeckal G. Harikumar, Sarah J. Piper, Sweta Raval, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton and Laurence J. Miller

Molecular Pharmacology June 2022, 101 (6) 400-407; DOI: https://doi.org/10.1124/molpharm.122.000502
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Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake
Vusumuzi N. Hove, Kenneth Anderson, Elizabeth R. Hayden, Kyle Z. Pasquariello, Alice A. Gibson, Shichen Shen, Jun Qu, Yan Jin, Jeffrey C. Miecznikowski, Shuiying Hu and Jason A. Sprowl

Molecular Pharmacology June 2022, 101 (6) 381-389; DOI: https://doi.org/10.1124/molpharm.121.000287
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The Synthetic Cannabinoid WIN55,212-2 Can Disrupt the Golgi Apparatus Independent of Cannabinoid Receptor-1
Joshua Lott, Emily M. Jutkiewicz and Manojkumar A. Puthenveedu

Molecular Pharmacology May 2022, 101 (5) 371-380; DOI: https://doi.org/10.1124/molpharm.121.000377
Open Access
Influence of the TARP γ8-Selective Negative Allosteric Modulator JNJ-55511118 on AMPA Receptor Gating and Channel Conductance
Ian D. Coombs, Craig A. Sexton, Stuart G. Cull-Candy and Mark Farrant

Molecular Pharmacology May 2022, 101 (5) 343-356; DOI: https://doi.org/10.1124/molpharm.121.000473

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