Latest Articles

Article Type

Open Access
Naturally Occurring Mutations to Muscle-Type Creatine Kinase Impact Its Canonical and Pharmacological Activities in a Substrate-Dependent Manner In Vitro
Eric P. Mosher, Colten D. Eberhard and Namandjé N. Bumpus

Molecular Pharmacology December 2021, 100 (6) 588-596; DOI: https://doi.org/10.1124/molpharm.121.000348
You have access
Potential Use of Senolytics for Pharmacological Targeting of Precancerous Lesions
Tareq Saleh and Valerie J. Carpenter

Molecular Pharmacology December 2021, 100 (6) 580-587; DOI: https://doi.org/10.1124/molpharm.121.000361
You have access
Tacrine Induces Endoplasmic Reticulum–Stressed Apoptosis via Disrupting the Proper Assembly of Oligomeric Acetylcholinesterase in Cultured Neuronal Cells
Etta Y.L. Liu, Shinghung Mak, Xiangpeng Kong, Yingjie Xia, Kenneth K.L. Kwan, Miranda L. Xu and Karl W.K. Tsim

Molecular Pharmacology November 2021, 100 (5) 456-469; DOI: https://doi.org/10.1124/molpharm.121.000269
You have access
Therapeutic Neuroprotection by an Engineered Neurotrophin that Selectively Activates Tropomyosin Receptor Kinase (Trk) Family Neurotrophin Receptors but Not the p75 Neurotrophin Receptor
Fouad Brahimi, Alba Galan, Sairey Siegel, Stephanie Szobota, Marinko V. Sarunic, Alan C. Foster and H. Uri Saragovi

Molecular Pharmacology November 2021, 100 (5) 491-501; DOI: https://doi.org/10.1124/molpharm.121.000301
You have access
Construction and Characterization of CRISPR/Cas9 Knockout Rat Model of Carboxylesterase 2a Gene
Jie Liu, Xuyang Shang, Shengbo Huang, Yuan Xu, Jian Lu, Yuanjin Zhang, Zongjun Liu and Xin Wang

Molecular Pharmacology November 2021, 100 (5) 480-490; DOI: https://doi.org/10.1124/molpharm.121.000357
Open Access
Unique Positive Cooperativity Between the β-Arrestin–Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor
Biswaranjan Pani, Seungkirl Ahn, Paula K. Rambarat, Shashank Vege, Alem W. Kahsai, Andrew Liu, Bruno N. Valan, Dean P. Staus, Tommaso Costa and Robert J. Lefkowitz

Molecular Pharmacology November 2021, 100 (5) 513-525; DOI: https://doi.org/10.1124/molpharm.121.000363
You have access
Membrane-Mediated Activity of Local Anesthetics
Stephan L. Grage, Anke Culetto, Anne S. Ulrich and Stefan Weinschenk

Molecular Pharmacology November 2021, 100 (5) 502-512; DOI: https://doi.org/10.1124/molpharm.121.000252
You have access
Regulation of Adrenergic, Serotonin, and Dopamine Receptors to Inhibit Diabetic Retinopathy: Monotherapies versus Combination Therapies
Timothy S. Kern, Yunpeng Du, Jie Tang, Chieh Allen Lee, Haitao Liu, Alyssa Dreffs, Henri Leinonen, David A. Antonetti and Krzysztof Palczewski

Molecular Pharmacology November 2021, 100 (5) 470-479; DOI: https://doi.org/10.1124/molpharm.121.000278
You have access
Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77)
Vivek Krishna Pulakazhi Venu, Mahmoud Saifeddine, Koichiro Mihara, Muniba Faiza, Evgueni Gorobets, Andrew J. Flewelling, Darren J. Derksen, Simon A. Hirota, Isra Marei, Dana Al-Majid, Majid Motahhary, Hong Ding, Chris R. Triggle and Morley D. Hollenberg

Molecular Pharmacology November 2021, 100 (5) 428-455; DOI: https://doi.org/10.1124/molpharm.120.000148
You have access
Membrane-Facilitated Receptor Access and Binding Mechanisms of Long-Acting β2-Adrenergic Receptor Agonists
Christopher T. Szlenk, Jeevan B. GC and Senthil Natesan

Molecular Pharmacology October 2021, 100 (4) 406-427; DOI: https://doi.org/10.1124/molpharm.121.000285

Main menu

User menu

Search

Latest Articles

Pages

Navigate

More Information

ASPET's Other Journals