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A Recombinant Dimethylarginine Dimethylaminohydrolase-1–Based Biotherapeutics to Pharmacologically Lower Asymmetric Dimethyl Arginine, thus Improving Postischemic Cardiac Function and Cardiomyocyte Mitochondrial Activity
Young Lee, Jaipal Singh, Susan R. Scott, Bradley Ellis, Pinar Zorlutuna and Meijing Wang

Molecular Pharmacology April 2022, 101 (4) 226-235; DOI: https://doi.org/10.1124/molpharm.121.000394
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Yeast β-glucan Increases Etoposide Sensitivity in Lung Cancer Cell Line A549 by Suppressing Nuclear Factor Erythroid 2-Related Factor 2 via the Noncanonical Nuclear Factor Kappa B Pathway
Ferbian Milas Siswanto, Akiyoshi Tamura, Rika Sakuma and Susumu Imaoka

Molecular Pharmacology April 2022, 101 (4) 257-273; DOI: https://doi.org/10.1124/molpharm.121.000475
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Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors
Jon Merlin, Julia Park, Teresa H. Vandekolk, Stewart A. Fabb, Jeanne Allinne, Roger J. Summers, Christopher J. Langmead and Darren M. Riddy

Molecular Pharmacology April 2022, 101 (4) 246-256; DOI: https://doi.org/10.1124/molpharm.121.000422
Open Access
Degraders: The Ultimate Weapon Against Amplified Driver Kinases in Cancer
Pedro Torres-Ayuso and John Brognard

Molecular Pharmacology April 2022, 101 (4) 191-200; DOI: https://doi.org/10.1124/molpharm.121.000306
Open Access
G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 Regulation
Chase H. Melick, Tshering D. Lama-Sherpa, Adna Curukovic and Jenna L. Jewell

Molecular Pharmacology April 2022, 101 (4) 181-190; DOI: https://doi.org/10.1124/molpharm.121.000302
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A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient K_V11.1 (hERG) Variants
Christian L. Egly, Daniel J. Blackwell, Jeffrey Schmeckpeper, Brian P. Delisle, C. David Weaver and Björn C. Knollmann

Molecular Pharmacology April 2022, 101 (4) 236-245; DOI: https://doi.org/10.1124/molpharm.121.000421
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mTOR Regulation of AGC Kinases: New Twist to an Old Tail
Timothy R. Baffi and Alexandra C. Newton

Molecular Pharmacology April 2022, 101 (4) 213-218; DOI: https://doi.org/10.1124/molpharm.121.000310
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Senolytic-Mediated Elimination of Head and Neck Tumor Cells Induced Into Senescence by Cisplatin
Fereshteh Ahmadinejad, Tasia Bos, Bin Hu, Erin Britt, Jennifer Koblinski, Andrew J. Souers, Joel D. Leverson, Anthony C. Faber, David A. Gewirtz and Hisashi Harada

Molecular Pharmacology March 2022, 101 (3) 168-180; DOI: https://doi.org/10.1124/molpharm.121.000354
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New Synthetic Caffeine Analogs as Modulators of the Cholinergic System
Camila Fabiani, Brunella Biscussi, Juan P. Munafó, Ana P. Murray, Jeremías Corradi and Silvia S. Antollini

Molecular Pharmacology March 2022, 101 (3) 154-167; DOI: https://doi.org/10.1124/molpharm.121.000415
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Roles of Receptor Phosphorylation and Rab Proteins in G Protein-Coupled Receptor Function and Trafficking
Juan Carlos Martínez-Morales, M. Teresa Romero-Ávila, Guadalupe Reyes-Cruz and Jesús Adolfo García-Sáinz

Molecular Pharmacology March 2022, 101 (3) 144-153; DOI: https://doi.org/10.1124/molpharm.121.000429

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