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Molecular Pharmacology

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Latest Articles

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    Differential Enantiomer-Specific Signaling of Cannabidiol at CB1 Receptors
    Taryn Bosquez-Berger, Sierra Wilson, Christos Iliopoulos-Tsoutsouvas, Shan Jiang, Jim Wager-Miller, Spyros P. Nikas, Ken P. Mackie, Alexandros Makriyannis and Alex Straiker
    Molecular Pharmacology December 2022, 102 (6) 259-268; DOI: https://doi.org/10.1124/molpharm.121.000305
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    Cancer-Type Organic Anion Transporting Polypeptide 1B3 Is Localized in Lysosomes and Mediates Resistance against Kinase Inhibitors
    Bastian Haberkorn, Stefan Oswald, Niklas Kehl, Arne Gessner, R. Verena Taudte, Jan Philipp Dobert, Friederike Zunke, Martin F. Fromm and Jörg König
    Molecular Pharmacology December 2022, 102 (6) 248-258; DOI: https://doi.org/10.1124/molpharm.122.000539
  • Structural Basis for the Allosteric Inhibition of Hypoxia-Inducible Factor 2 by Belzutifan
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    Structural Basis for the Allosteric Inhibition of Hypoxia-Inducible Factor 2 by Belzutifan
    Xintong Ren, Xiaotong Diao, Jingjing Zhuang and Dalei Wu
    Molecular Pharmacology December 2022, 102 (6) 240-247; DOI: https://doi.org/10.1124/molpharm.122.000525
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    The Emerging Structural Pharmacology of ATP-Sensitive Potassium Channels
    Jing-Xiang Wu, Dian Ding and Lei Chen
    Molecular Pharmacology November 2022, 102 (5) 234-239; DOI: https://doi.org/10.1124/molpharm.122.000570
  • Open Access
    Inhibition of the Aromatase Enzyme by Exemestane Cysteine Conjugates
    Irina Teslenko, Christy J.W. Watson, Gang Chen and Philip Lazarus
    Molecular Pharmacology November 2022, 102 (5) 216-222; DOI: https://doi.org/10.1124/molpharm.122.000545
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    Pore Opening, Not Voltage Sensor Movement, Underpins the Voltage-Dependence of Facilitation by a hERG Blocker
    Kazuharu Furutani, Ryotaro Kawano, Minami Ichiwara, Ryo Adachi, Colleen E. Clancy, Jon T. Sack and Satomi Kita
    Molecular Pharmacology November 2022, 102 (5) 223-233; DOI: https://doi.org/10.1124/molpharm.122.000569
  • Upacicalcet Is a Novel Secondary Hyperparathyroidism Drug that Targets the Amino Acid Binding Site of Calcium-Sensing Receptor 
    Open Access
    Upacicalcet Is a Novel Secondary Hyperparathyroidism Drug that Targets the Amino Acid Binding Site of Calcium-Sensing Receptor 
    Hirofumi Sato, Sei Murakami, Yusuke Horii, Go Nishimura, Ryosuke Iwai, Moritaka Goto and Naoki Takahashi
    Molecular Pharmacology October 2022, 102 (4) 183-195; DOI: https://doi.org/10.1124/molpharm.122.000522
  • Analgesic α-Conotoxin Binding Site on the Human GABA<sub>B</sub> Receptor
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    Analgesic α-Conotoxin Binding Site on the Human GABAB Receptor
    Anuja R. Bony, Jeffrey R. McArthur, Akari Komori, Ann R. Wong, Andrew Hung and David J. Adams
    Molecular Pharmacology October 2022, 102 (4) 196-208; DOI: https://doi.org/10.1124/molpharm.122.000543
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    Extrachromosomal Circular DNAs, Amplified Oncogenes, and CRISPR-Cas9 System
    Fatemeh Pourrajab and Mohamad Reza Zare-Khormizi
    Molecular Pharmacology October 2022, 102 (4) 209-215; DOI: https://doi.org/10.1124/molpharm.122.000553
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    Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads
    Michelle M. Butler, Samanthi L. Waidyarachchi, Jinfeng Shao, Son T. Nguyen, Xiaoyuan Ding, Steven C. Cardinale, Lucas R. Morin, Steven M. Kwasny, Mai Ito, Jeanine Gezelle, María B. Jiménez-Díaz, Iñigo Angulo-Barturen, Robert T. Jacobs, Jeremy N. Burrows, Zachary D. Aron, Terry L. Bowlin and Sanjay A. Desai
    Molecular Pharmacology September 2022, 102 (3) 172-182; DOI: https://doi.org/10.1124/molpharm.122.000549

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