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Differential Enantiomer-Specific Signaling of Cannabidiol at CB₁ Receptors
Taryn Bosquez-Berger, Sierra Wilson, Christos Iliopoulos-Tsoutsouvas, Shan Jiang, Jim Wager-Miller, Spyros P. Nikas, Ken P. Mackie, Alexandros Makriyannis and Alex Straiker

Molecular Pharmacology December 2022, 102 (6) 259-268; DOI: https://doi.org/10.1124/molpharm.121.000305
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Cancer-Type Organic Anion Transporting Polypeptide 1B3 Is Localized in Lysosomes and Mediates Resistance against Kinase Inhibitors
Bastian Haberkorn, Stefan Oswald, Niklas Kehl, Arne Gessner, R. Verena Taudte, Jan Philipp Dobert, Friederike Zunke, Martin F. Fromm and Jörg König

Molecular Pharmacology December 2022, 102 (6) 248-258; DOI: https://doi.org/10.1124/molpharm.122.000539
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Structural Basis for the Allosteric Inhibition of Hypoxia-Inducible Factor 2 by Belzutifan
Xintong Ren, Xiaotong Diao, Jingjing Zhuang and Dalei Wu

Molecular Pharmacology December 2022, 102 (6) 240-247; DOI: https://doi.org/10.1124/molpharm.122.000525
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The Emerging Structural Pharmacology of ATP-Sensitive Potassium Channels
Jing-Xiang Wu, Dian Ding and Lei Chen

Molecular Pharmacology November 2022, 102 (5) 234-239; DOI: https://doi.org/10.1124/molpharm.122.000570
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Inhibition of the Aromatase Enzyme by Exemestane Cysteine Conjugates
Irina Teslenko, Christy J.W. Watson, Gang Chen and Philip Lazarus

Molecular Pharmacology November 2022, 102 (5) 216-222; DOI: https://doi.org/10.1124/molpharm.122.000545
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Pore Opening, Not Voltage Sensor Movement, Underpins the Voltage-Dependence of Facilitation by a hERG Blocker
Kazuharu Furutani, Ryotaro Kawano, Minami Ichiwara, Ryo Adachi, Colleen E. Clancy, Jon T. Sack and Satomi Kita

Molecular Pharmacology November 2022, 102 (5) 223-233; DOI: https://doi.org/10.1124/molpharm.122.000569
Open Access
Upacicalcet Is a Novel Secondary Hyperparathyroidism Drug that Targets the Amino Acid Binding Site of Calcium-Sensing Receptor
Hirofumi Sato, Sei Murakami, Yusuke Horii, Go Nishimura, Ryosuke Iwai, Moritaka Goto and Naoki Takahashi

Molecular Pharmacology October 2022, 102 (4) 183-195; DOI: https://doi.org/10.1124/molpharm.122.000522
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Analgesic α-Conotoxin Binding Site on the Human GABA_B Receptor
Anuja R. Bony, Jeffrey R. McArthur, Akari Komori, Ann R. Wong, Andrew Hung and David J. Adams

Molecular Pharmacology October 2022, 102 (4) 196-208; DOI: https://doi.org/10.1124/molpharm.122.000543
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Extrachromosomal Circular DNAs, Amplified Oncogenes, and CRISPR-Cas9 System
Fatemeh Pourrajab and Mohamad Reza Zare-Khormizi

Molecular Pharmacology October 2022, 102 (4) 209-215; DOI: https://doi.org/10.1124/molpharm.122.000553
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Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads
Michelle M. Butler, Samanthi L. Waidyarachchi, Jinfeng Shao, Son T. Nguyen, Xiaoyuan Ding, Steven C. Cardinale, Lucas R. Morin, Steven M. Kwasny, Mai Ito, Jeanine Gezelle, María B. Jiménez-Díaz, Iñigo Angulo-Barturen, Robert T. Jacobs, Jeremy N. Burrows, Zachary D. Aron, Terry L. Bowlin and Sanjay A. Desai

Molecular Pharmacology September 2022, 102 (3) 172-182; DOI: https://doi.org/10.1124/molpharm.122.000549

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