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Modulation of Kv7 Channel Currents by Echinocystic Acid
DanDan Geng, Yaning Li, Rong Zheng, Runmeng Wang, Bo Yang, Huaxing Zhang, Yang Zhang and Fan Zhang

Molecular Pharmacology August 2023, 104 (2) 42-50; DOI: https://doi.org/10.1124/molpharm.122.000640
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The Potential Antidepressant Compound Org 34167 Modulates HCN Channels Via a Novel Mode of Action
Chaseley E. McKenzie, Andrew Hung, A. Marie Phillips, Ming S. Soh, Christopher A. Reid and Ian C. Forster

Molecular Pharmacology August 2023, 104 (2) 62-72; DOI: https://doi.org/10.1124/molpharm.123.000676
Open Access
Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56
Alexander L. Vizurraga, Michael J. Robertson, Maiya Yu, Georgios Skiniotis and Gregory G. Tall

Molecular Pharmacology July 2023, 104 (1) 28-41; DOI: https://doi.org/10.1124/molpharm.123.000688
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Multiomics Analyses Identify Proline Endopeptidase–Like Protein As a Key Regulator of Protein Trafficking, a Pathway Underlying Alzheimer’s Disease Pathogenesis
Mariana Lemos Duarte, Minghui Wang, Ivone Gomes, Chenge Liu, Ali Sharma, Amanda K. Fakira, Achla Gupta, Seshat M. Mack, Bin Zhang and Lakshmi A. Devi

Molecular Pharmacology July 2023, 104 (1) 1-16; DOI: https://doi.org/10.1124/molpharm.122.000641
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Differential Activity of Orthosteric Agonists and Allosteric Modulators at Metabotropic Glutamate Receptor 7
Xia Lei, Christopher S. Hofmann, Alice L. Rodriguez and Colleen M. Niswender

Molecular Pharmacology July 2023, 104 (1) 17-27; DOI: https://doi.org/10.1124/molpharm.123.000678
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Rigorous Characterization of Allosteric Modulation of the Human Metabotropic Glutamate Receptor 1 Reveals Probe- and Assay-Dependent Pharmacology
Ashwin Muraleetharan, Yuyang Wang, Matthew C. Rowe, Ashleigh Gould, Karen J. Gregory and Shane D. Hellyer

Molecular Pharmacology June 2023, 103 (6) 325-338; DOI: https://doi.org/10.1124/molpharm.122.000664
Open Access
Determinants of Subtype-Selectivity of the Anthelmintic Paraherquamide A on Caenorhabditis elegans Nicotinic Acetylcholine Receptors
Wataru Koizumi, Shuya Otsubo, Shogo Furutani, Kunihiro Niki, Koichi Takayama, Shota Fujimura, Takanobu Maekawa, Ryosuke Koyari, Makoto Ihara, Kenji Kai, Hideo Hayashi, Mohammad Shaokat Ali, Eriko Kage-Nakadai, David B. Sattelle and Kazuhiko Matsuda

Molecular Pharmacology June 2023, 103 (6) 299-310; DOI: https://doi.org/10.1124/molpharm.122.000601
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In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A_2A Receptor Antagonist/Inverse Agonist
Yutaro Ohno, Michihiko Suzuki, Hidetsugu Asada, Tomoyuki Kanda, Mayumi Saki, Hikaru Miyagi, Mai Yasunaga, Chiyo Suno, So Iwata, Jun-ichi Saito and Shinichi Uchida

Molecular Pharmacology June 2023, 103 (6) 311-324; DOI: https://doi.org/10.1124/molpharm.122.000633
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Human α6β4 Nicotinic Acetylcholine Receptor: Heterologous Expression and Agonist Behavior Provide Insights into the Immediate Binding Site
María Constanza Maldifassi, Hugo Rego Campello, Timothy Gallagher, Henry A. Lester and Dennis A. Dougherty

Molecular Pharmacology June 2023, 103 (6) 339-347; DOI: https://doi.org/10.1124/molpharm.123.000672
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Aryl Hydrocarbon Receptor as a Therapeutical Target of Environmentally Induced Skin Conditions
Caroline de Almeida Freitas Accioli, Michelle Sabrina da Silva, Bianca Aloise Maneira Corrêa Santos and Carlos Rangel Rodrigues

Molecular Pharmacology May 2023, 103 (5) 255-265; DOI: https://doi.org/10.1124/molpharm.122.000627

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