Abstract
Precipitating antibodies were prepared against the determinant phenoxycholine, a nicotinic agonist. The affinity of the antibody for a wide range of agonists and antagonists related to acetylcholine was tested. The affinity constants were found to range between 3.2 x 105 and 6.9 x 103 M-1. The antibody did not discriminate between agonists and antagonists, or between drugs acting at muscarinic and nicotinic receptors.
- Copyright ©, 1969, by Academic Press Inc.
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