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Molecular Pharmacology

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Research ArticleArticle

Identification of PKC Activation as a Novel Mechanism for RGS2 Protein Up-regulation Through Phenotypic Screening of Natural Product Extracts

Avi Raveh, Pamela J. Schultz, Lauren Aschermann, Colleen Carpenter, Giselle Tamayo-Castillo, Shugeng Cao, Jon Clardy, Richard R Neubig, David H Sherman and Benita Sjogren
Molecular Pharmacology August 1, 2014, mol.114.092403; DOI: https://doi.org/10.1124/mol.114.092403
Avi Raveh
1 University of Michigan;
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Pamela J. Schultz
1 University of Michigan;
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Lauren Aschermann
2 Michigan State University;
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Colleen Carpenter
1 University of Michigan;
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Giselle Tamayo-Castillo
3 Instituto Nacional de Biodiversidad;
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Shugeng Cao
4 Harvard Medical School
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Jon Clardy
4 Harvard Medical School
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Richard R Neubig
2 Michigan State University;
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David H Sherman
1 University of Michigan;
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Benita Sjogren
2 Michigan State University;
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Data Supplement

Files in this Data Supplement:

  • Supplemental Data -

    Supplemental Methods - 16S rDNA PCR Amplification, Cloning, and Sequencing

    Supplemental Figure 1 - Schematic presentation of the screening strategy to identify natural products that increase RGS2 protein levels

    Supplemental Figure 2 - Decision tree of high-throughput screen follow-up

  View article

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