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Molecular Pharmacology

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Research ArticleArticle

Identification of AICP as a GluN2C-selective NMDA receptor superagonist at the GluN1 glycine site

Maja Jessen, Kristen Frederiksen, Feng Yi, Rasmus P Clausen, Kasper B Hansen, Hans Brauner-Osborne, Paul Kilburn and Anders Damholt
Molecular Pharmacology June 6, 2017, mol.117.108944; DOI: https://doi.org/10.1124/mol.117.108944
Maja Jessen
1 University of Copenhagen;
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Kristen Frederiksen
2 H. Lundbeck;
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Feng Yi
3 University of Montana;
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Rasmus P Clausen
1 University of Copenhagen;
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Kasper B Hansen
3 University of Montana;
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Hans Brauner-Osborne
1 University of Copenhagen;
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Paul Kilburn
2 H. Lundbeck;
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Anders Damholt
4 Chr. Hansen
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Data Supplement

  • Supplemental Tables -

    Supplemental Table 1. Influence of glutamate concentrations on AICP concentration-response data at rat

    NMDA receptor subtypes.

    Supplemental Table 2. Concentration-response data for AICP and DCS at wild type and mutant rat

    GluN1/2A and GluN1/2C receptors.

    Supplemental Table 3. Concentration-response data for AICP at human NMDA receptor subtypes in the

    presence of glycine.

    Supplemental Table 4. Concentration-response data for AICP and DCS at mutant and chimeric

    GluN1/2A, GluN1/2B, and GluN1/2C receptors.

  View article

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