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Molecular Pharmacology

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Research ArticleArticle

G protein pre-assembly rescues efficacy of W6.48 toggle mutations in neuropeptide Y2 receptor

Anette Kaiser, Caroline Hempel, Lizzy Wanka, Mario Schubert, Heidi E. Hamm and Annette G. Beck-Sickinger
Molecular Pharmacology February 7, 2018, mol.117.110544; DOI: https://doi.org/10.1124/mol.117.110544
Anette Kaiser
1 Institute of Biochemistry, Leipzig University;
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Caroline Hempel
2 Institute of Clinical Physiology, Charite Berlin;
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Lizzy Wanka
1 Institute of Biochemistry, Leipzig University;
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Mario Schubert
1 Institute of Biochemistry, Leipzig University;
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Heidi E. Hamm
3 Department of Pharmacology, Vanderbilt University Medical Center
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Annette G. Beck-Sickinger
1 Institute of Biochemistry, Leipzig University;
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Data Supplement

  • Supplemental Figures -

    Supplemental Figure 1 - Surface expression of Y2R W6.48 variants

    Supplemental Figure 2 - Functionality verification of Venus-tagged G-alpha subunits

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