TY - JOUR T1 - Comparative Inhibitory Action of D- and L-Tryptophan on the Effect of <em>d</em>-Lysergic Acid Diethylamide <em>in Vitro</em> JF - Molecular Pharmacology JO - Mol Pharmacol SP - 68 LP - 77 VL - 10 IS - 1 AU - JEFFREY L. WINKELHAKE AU - EDWARD W. VOSS, JR. AU - DENNIS E. LOPATIN Y1 - 1974/01/01 UR - http://molpharm.aspetjournals.org/content/10/1/68.abstract N2 - The incorporation in vitro of d-[3H]lysergic acid diethylamide into secreted protein from hyperimmune rabbit lymphoid cells was inhibited by both D- and L-tryptophan. The inhibition was specific for tryptophan isomers and analogues. On the basis of these findings a pathway was formulated to describe the preliminary steps culminating in the covalent incorporation of lysergic acid diethylamide into synthesized protein. ER -