PT - JOURNAL ARTICLE AU - BRESNICK, EDWARD AU - HASSUK, BRUCE AU - LIBERATOR, PAUL AU - LEVIN, WAYNE AU - THOMAS, PAUL E. TI - Nucleolar Cytochrome <em>P</em>-450 DP - 1980 Nov 01 TA - Molecular Pharmacology PG - 550--552 VI - 18 IP - 3 4099 - http://molpharm.aspetjournals.org/content/18/3/550.short 4100 - http://molpharm.aspetjournals.org/content/18/3/550.full SO - Mol Pharmacol1980 Nov 01; 18 AB - Significant amounts of cytochrome P-450 have been detected spectrally in purified nucleoli obtained from the livers of 3-methylcholanthrene-treated rats. Using monospecific antibody to microsomal cytochrome P-450c (P-448), we have shown that the nucleolar and microsomal enzymes are immunochemically identical. These nucleoli also contained epoxide hydrolase and NADPH-cytochrome c reductase activities, both of which were immunochemically identical to their respective microsomal counterparts.