PT  - JOURNAL ARTICLE
AU  - MENEK GOLDSTEIN
AU  - TONG HYUB JOH
TI  - The Effect of Reduced and Oxidized Pteridine on Dopamine-β-Hydroxylase Activity
DP  - 1967 Jul 01
TA  - Molecular Pharmacology
PG  - 396--398
VI  - 3
IP  - 4
4099  - http://molpharm.aspetjournals.org/content/3/4/396.short
4100  - http://molpharm.aspetjournals.org/content/3/4/396.full
SO  - Mol Pharmacol1967 Jul 01; 3
AB  - Tetrahydropteridine (DMPH4) reacts with dopamine-β-hydroxylase anaerobically and forms a reduced enzyme intermediate which aerobically catalyzes the β-hydroxylation of tyramine-3H. Under aerobic conditions DMPH4, in combination with NADH, is effective in the stimulation of enzymic β-hydroxylation. Oxidized DMPH4 inhibits the enzymic activity.