PT - JOURNAL ARTICLE AU - Lee E. Eiden TI - Fusion Polypeptides That Inhibit Exocytosis: Fusing Aptamer and Cell-Penetrating Peptide Technologies and Pharmacologies AID - 10.1124/mol.105.011429 DP - 2005 Apr 01 TA - Molecular Pharmacology PG - 980--982 VI - 67 IP - 4 4099 - http://molpharm.aspetjournals.org/content/67/4/980.short 4100 - http://molpharm.aspetjournals.org/content/67/4/980.full SO - Mol Pharmacol2005 Apr 01; 67 AB - Cell-penetrating peptides are amphipathic or cationic oligopeptides able to transport covalently attached cargoes across cell membranes. Peptide aptamers are polypeptide fragments of endogenous proteins that mimic and thus perturb interactions with other cellular proteins. Combining aptamer and CPP technology can generate pharmacological reagents effective in cell culture models and in vivo.