PT - JOURNAL ARTICLE AU - Olivier Civelli TI - An Orphan Receptor Adopted by a Family of Transmitters AID - 10.1124/mol.104.010348 DP - 2005 Mar 01 TA - Molecular Pharmacology PG - 583--584 VI - 67 IP - 3 4099 - http://molpharm.aspetjournals.org/content/67/3/583.short 4100 - http://molpharm.aspetjournals.org/content/67/3/583.full SO - Mol Pharmacol2005 Mar 01; 67 AB - A tenet of pharmacology states that a receptor must be selective for and bind its natural ligand with high affinity. Recently discovered ligands of some deorphanized G protein-coupled receptors challenge this concept.