TY - JOUR T1 - The Complex Roles of <em>μ</em>-Opioid Receptor Phosphorylation: A Key Determinant in Receptor Signaling and Regulation JF - Molecular Pharmacology JO - Mol Pharmacol SP - 814 LP - 815 DO - 10.1124/mol.115.100180 VL - 88 IS - 4 AU - Meritxell Canals Y1 - 2015/10/01 UR - http://molpharm.aspetjournals.org/content/88/4/814.abstract N2 - This Commentary focuses on two articles in the October 2015 issue of Molecular Pharmacology that investigate the role of μ-opioid receptor phosphorylation in receptor agonist binding and desensitization. The work of Birdsong et al. and Yousuf et al. clearly highlights the complexity that researchers face when trying to assess the signaling and regulatory consequences of G protein–coupled receptor phosphorylation. ER -