PT  - JOURNAL ARTICLE
AU  - Zijian Li
TI  - A Chinese Perspective on Receptors and Receptor Regulation
AID  - 10.1124/mol.117.109587
DP  - 2017 Sep 01
TA  - Molecular Pharmacology
PG  - 185--187
VI  - 92
IP  - 3
4099  - http://molpharm.aspetjournals.org/content/92/3/185.short
4100  - http://molpharm.aspetjournals.org/content/92/3/185.full
SO  - Mol Pharmacol2017 Sep 01; 92
AB  - A receptor is a protein molecule that receives chemical signals from outside a cell, which enables the cell to respond to the signal molecule. Receptors mediate numerous important physiologic effects upon binding extracellular agonists. However, sustained activation of the receptor may lead to pathologic effects. Cells can regulate the number and function of receptors to alter their sensitivity to different molecules by a feedback mechanism, such as change in the receptor conformation, uncoupling of the receptor effector molecules, receptor sequestration, etc. In this special issue, some Chinese scientists were invited to contribute impactful discoveries and insightful reviews in the field of molecular pharmacology, especially receptor and receptor regulation.