PT  - JOURNAL ARTICLE
AU  - von Zastrow, Mark
TI  - <strong>Proteomic approaches to investigate regulated trafficking and signaling of GPCRs</strong>
AID  - 10.1124/molpharm.120.000178
DP  - 2020 Jan 01
TA  - Molecular Pharmacology
PG  - MOLPHARM-MR-2020-000178
4099  - http://molpharm.aspetjournals.org/content/early/2020/12/22/molpharm.120.000178.short
4100  - http://molpharm.aspetjournals.org/content/early/2020/12/22/molpharm.120.000178.full
AB  - Advances in proteomic methodologies based on quantitative mass spectrometry are now transforming pharmacology and experimental biology more broadly. The present review will discuss several examples, based on work in the author's laboratory that focuses on delineating relationships between GPCR signaling and trafficking in the endocytic network. The examples highlighted correspond to those discussed in a talk presented at the 2019 EB/ASPET meeting, organized by Professor Joe Beavo to commemorate his receipt of the Julius Axelrod Award. Significance Statement This is a review related to the EB2019 Axelrod Symposium.