K i reversal values for substrates and antagonists
| NSC | Ki reversal |
|---|---|
| Substrate | |
| 38270 (S) | >100 |
| 328426 (S) | 5.44 |
| 339281 (S) | 2.55 |
| 359449 (S) | >100 |
| 630176 (S) | >100 |
| 633043 (S) | >100 |
| 640085 (S) | >100 |
| 666490 (S) | >100 |
| Antagonist | |
| 68075 (A) | 0.37 |
| 665333 (A) | 0.28 |
| 667739 (A) | 5.13 |
| 676590 (A) | 1.42 |
| 676591 (A) | 0.28 |
| 676597 (A) | 0.62 |
| 676599 (A) | 2.18 |
| 676600 (A) | 0.06 |
| Overlap | |
| 676605 (O) | 0.48 |
| 668360 (O) | 0.25 |
K i reversal is the concentration (μm) at which half of the Pgp-mediated transport is blocked.