Table 1

Concentration dependence of opioid agonists

DrugCurrent evoked by 100 μMCurrent amplitude
3 μm10 μm30 μm300 μm
pA % of that induced by 100 μm
ME366  ± 58 (11)67  ± 12 (3)91  ± 4 (8)
DSLET316  ± 44 (12)69  ± 7 (6)101  ± 0.5 (6)
DAMGO283  ± 28 (13)86  ± 5 (3)93  ± 2 (10)