Table 1

[3H]NMS binding to membranes of CHO cells expressing human m1-m4 muscarinic receptor genes: Kd andB max values

Receptor subtypeKNMS Bmax
pm fmol/106 cells
M1 103  ± 7111  ± 11
M2 148  ± 485  ± 12
M3 119  ± 6143  ± 10
M4 107  ± 4129  ± 9

Data are mean ± standard error of three experiments with triplicate incubations.