Table 3

Rat nucleus accumbens: displacement of [125I]amylin

AntagonistMean pKi AgonistMean pKi
AC51210.5  ± 0.30rAMYLIN10.29  ± 0.15
(n = 4)(n = 6)
AC669.12  ± 0.45Rat CAL6.0  ± 0.08
(n = 5)(n = 4)
AC4139.77  ± 0.32hCAL6.2  ± 0.05
(n = 5)(n = 5)
hCGRP8–37 8.31  ± 0.37rCGRP9.81  ± 0.54
(n = 5)(n = 6)
Eel CAL10.5  ± 0.3
(n = 4)