MCF-7 cells: displacement of [125I]AC512
| Antagonist | pKi | Agonist | pKi high | pKi low | H |
|---|---|---|---|---|---|
| % | |||||
| AC512 | 10.0 ± 0.03 | rAMYLIN | 9.85 ± 0.15 | 7.75 ± 0.12 | 46 |
| (n = 6) | (n = 4) | ||||
| AC66 | 10.28 ± 0.05 | Rat CAL | 9.0 ± 0.05 | 6.9 ± 0.07 | 36 |
| (n = 6) | (n = 4) | ||||
| AC413 | N.D. | hCAL | 8.73 ± 0.15 | 6.83 ± 0.23 | 67 |
| (n = 4) | |||||
| hCGRP8–37 | 6.73 ± 0.03 | rCGRP | 9.29 ± 0.04 | 7.74 ± 0.02 | 55 |
| (n = 5) | (n = 4) | ||||