Table 4

Inhibition of spontaneous mutant receptors by GABA

CombinationIC50Hill coefficientOocytes
μm n
ρ1L301A0.12  ± 0.012.90  ± 1.026
ρ1L301G0.33  ± 0.063.83  ± 1.816
ρ1L301S0.18  ± 0.033.15  ± 0.756
ρ1L301T0.021  ± 0.0051.32  ± 0.076

Values are mean ± standard deviation.