Summary of curve fit parameters from results of experiments illustrated in Fig. 2
AA release | IP accumulation | |||
---|---|---|---|---|
Vehicle | 2 μm PBZ | Vehicle | 2 μm PBZ | |
Emax (%) | 162 ± 33 | 75 ± 4 | 324 ± 26 | 165 ± 33 |
pEC50(nm) | 7.22 ± 0.1 (60) | 7.24 ± 0.1 (75) | 7.21 ± 0.1 (62) | 7.14 ± 0.1 (72) |
Slope | 1.49 ± 0.21 | 1.83 ± 0.45 | 0.95 ± 0.12 | 1.23 ± 0.1 |