Table 5

Effects of L-DOPA, LNAC, and NGF on GSH synthesis

	GSH	Protein	GSH
	μg/well		μg/mg protein
Controls	1.68 ± 0.2 (100%)	993 ± 13 (100%)	1.69 ± 0.08 (100%)
L-DOPA	3.17 ± 0.1^5-150 (190%)	737 ± 18^5-150 (74%)	3.02 ± 0.06^5-150 (179%)
NGF	2.81 ± 0.2^5-150 (169%)	1270 ± 12^5-150 (128%)	2.21 ± 0.08^5-150 (131%)
L-DOPA & NGF	5.63 ± 0.01^5-150† (339%)	1460 ± 70^5-150† (147%)	3.86 ± 0.01^5-150† (228%)
LNAC	4.17 ± 0.2^5-150 (249%)	1290 ± 80^5-150 (130%)	3.23 ± 0.1^5-150 (191%)
L-DOPA & LNAC	5.03 ± 0.1^5-150† (300%)	1183 ± 60^5-160 (119%)	4.22 ± 0.1^5-150† (250%)

Five days after plating, cultures were exposed to 50 μmL-DOPA, 500 μm LNAC, or 50 ng/ml NGF for 24 hr. The cultures were then assayed for total GSH and protein levels. Data are mean ± standard error (n = 6).

↵5-150 p < 0.001 versus controls.
↵5-160 p < 0.01 versus controls.
^† p < 0.001 for cultures treated with L-DOPA & NGF versus L-DOPA, or treated with L-DOPA & LNAC versus L-DOPA.