α4:β2 ratio | EC50 | nH | Emax |
---|---|---|---|
μM | %1 mm ACh | ||
9:1 | 58.8 ± 14.7 | 1.33 ± 0.19 | 105.9 ± 2.7 |
1:1 | 65.6 ± 28.61-c | 1.14 ± 0.07 | 106.1 ± 2.5 |
1:11-a | 93.6 ± 14.71-c | 1.36 ± 0.15 | 105.8 ± 1.7 |
1:91-b | 1.84 ± 0.091-d | 1.05 ± 0.05 | 89.3 ± 6.0 |
For each experimental condition, three concentration-effect curves, each obtained from a different oocyte, were fitted, and the values represent mean ± standard deviation of the estimated parameters.