Table 1

Model rate constants

Rate ConstantControlα4S336Aβ2 (Fig. 7A)PMA (Fig.7D)Calphostin C (Fig. 7E)
min−1
k +0 500 μM−1
k −0 5000
k +1 500 μM−1
k −1 50
k +2 500 μM−1
k −2 0.5
d +1 24
d −1 0.24
d +2 0.0640.0320.128
d −2 0.00320.00107
l +1 0.5
l −1 0.5
l +2 0.006
l −2 0.030.010.060.015

Except where changes from control rate constants are shown, all rates remained unaltered.