Table 3

Effect of OA on cell cycle progression

Cell Line	Treatment	Apoptosis	G₀-G₁	G₂-M	S
		%	%	%	%
NIH3T3-parental	DMSO	0.79	77.23	16.59	6.18
	20 nM OA	2.83	74.65	22.06	3.59
NIH3T3-neo	DMSO	0.25	77.22	19.41	3.37
	20 nM OA	3.71	72.21	26.88	0.91
NIH3T3-ras	DMSO	1.25	76.79	16.49	6.72
	20 nM OA	23.18	62.01	37.99	0
SVHUC	DMSO	0.23	24.9	49.6	25.4
	OA	0.4	15.3	47.2	37.5
SVHUC-ras	DMSO	0.6	37.5	34.1	28.4
	OA	24.22	15.6	47.5	36.9

NIH3T3-parental, -ras and -neo cells were treated with 20 nM OA for 48 h whereas SVHUC and SVHUC-ras were treated for 24 h, and percentage of cells in various phases of the cell cycle was determined by flow cytometric analysis of PI-stained cells.