Table 2

Summary of antagonist properties

AntagonistIC50 (μM)nHN
PPADS0.63  ± 0.051.58
Suramin1.6  ± 0.70.68
TNP-ATP0.36  ± 0.130.68

IC50 was determined from a three-parameter (IC50,Imax, nH) curve fit to pooled data as described in Materials and Methods; estimates are expressed as mean ± S.D. N, number of cells contributing to the pooled data for each agonist.