Table 1

CB₁ and CB₂ cannabinoid receptor peptide fragments

Peptide^1-a	Sequence^1-b	Domain
CB₁1-14^1-c	MKSILDGLADTTFR(C)	CB₁receptor N terminus
CB₁174-188	(K)SFVDFHVFHRKDSPN	CB₁ receptor EL1
CB₁301-317	KAHSHAVRMIQRGTQKS	CB₁ receptor N side IL3
CB₁316-327	KS I I I HTSEDGK	CB₁ receptor middle IL3
CB₁329-344	QVTRPDQARMDIRLAK	CB₁receptor C side IL3
CB₁401-417	RSKDLRHAFRSMFPSSE	CB₁receptor C terminus (juxtamembrane)
CB₂302-320	RSGEIRSSAHHCLAHWKK	CB₂ receptor C terminus (juxtamembrane)

↵1-a The numbers correspond to inclusive amino acid residues of the sequences of the mouse CB₁ or human CB₂ cannabinoid receptors (see Howlett et al., 1998).
↵1-b Amino acids are shown in single letter code. Amino acids in parentheses were added to peptide sequences to facilitate coupling peptides to protein carriers. For peptide CB₁401-417, the underlined amino acid replaced a Cys in the sequence.
↵1-c Anti-CB₁1-14 was prepared using this peptide (Howlett et al., 1998).