Incidence of NAT1* genotypes in racially diverse groups1-a
| NAT1* Genotype1-b | Number Observed | Frequency |
|---|---|---|
| % total | ||
| Homozygotes | ||
| NAT1*4/*4 | 15 | 39.5 |
| NAT1*10/*10 | 2 | 5.3 |
| Heterozygotes | ||
| NAT1*4/*10 | 15 | 39.5 |
| NAT1*4/*11 | 2 | 5.3 |
| NAT1*4/*16 | 1 | 2.6 |
| Compound heterozygotes | ||
| NAT1*10/*11 | 2 | 5.3 |
| NAT1*10/*16 | 1 | 2.6 |
↵1-a 38 subjects: Caucasians, 12; Japanese, 5; mainland Chinese, 6; Koreans, 5; Asian Indians, 5; Hispanics, 5. TheNAT1* genotype of the Caucasian subjects is from a previous study (Vatsis and Weber, 1993).
↵1-b Determined by direct (no subcloning) sequencing of 1.6-kb fragments (nt −440 to 1175) of NAT1* amplified with leukocyte DNA as template (Vatsis and Weber, 1993).