Table 1

Effect of PTx on CCK-induced 1,4,5-IP3 and [Ca2+]i in AR42J cells

1,4,5-IP3 (pmol/mg protein)[Ca2+]i (nM)
BasalPeak (15 s)BasalPeak (10 s)
CCK (1 nM)51  ± 6253  ± 151-a 116  ± 12468  ± 251-a
CCK (1 nM) + PTx53  ± 8320  ± 241-a 1-b 128  ± 16550  ± 311-a 1-b

The data shown are means ± S.E. of three independent experiments.

    • ↵1-a Significant increase compared with the control (P < .05).

    • ↵1-b Significant effect of PTx treatment compared with the untreated control (P < .05).