Concentration-response parameters for A1 receptor agonist stimulation of cAMP accumulation (in the presence of 3 μM forskolin) after treatment of CHOA1H cells with PTX (24 h, 100 ng/ml)
| Agonist | Log EC50 | Maximum Response |
|---|---|---|
| M | (-fold over basal) | |
| CPA | −7.16 ± 0.24 (6) | 2.09 ± 0.12 (6) |
| NECA | −6.36 ± 0.15 (9) | 2.87 ± 0.32 (9) |
| R-PIA | −7.21 ± 0.22 (7) | 1.96 ± 0.13 (7) |
Values represent means ± S.E.M. from the number of experiments given in parentheses.